阿托伐他汀,依那普利,缬沙坦联合心理治疗对慢性肾炎患者的效果

Effect of atorvastatin,enalapril and valsartan combined with psychotherapy on patients with chronic nephritis

目的探讨阿托伐他汀,依那普利,缬沙坦联合心理治疗对慢性肾炎患者的治疗效果及其对患者抑郁,焦虑情绪的影响。方法选定本院2018年10月~2020年10月住院治疗的90例慢性肾炎患者,根据抽签法分组(每组n=45),参照组采纳阿托伐他汀+依那普利+缬沙坦治疗,观察组在参照组基础上联合心理治疗,比较两组临床疗效,汉密尔顿焦虑量表(HAMA)评分,汉密尔顿抑郁量表(HAMD)评分,患者满意度。结果观察组临床总有效率(95.56%)与参照组(91.11%)比较,P>0.05。观察组治疗后HAMA评分,HAMD评分均低于参照组,观察组患者满意度(95.56%)高于对比组(73.33%),差异均具有统计学意义(P<0.05)。结论阿托伐他汀,依那普利,缬沙坦联合心理治疗可有效改善慢性肾炎患者临床症状及心理状态,疗效确切,患者满意度较高。

Objective To analyze the therapeutic effect of atorvastatin,enalapril and valsartan combined with psychotherapy on patients with chronic nephritis and their effect on depression and anxiety.Methods 90 patients with chronic nephritis hospitalized in our hospital from October 2018 to October 2020 were selected and divided into groups according to the lottery method(n=45 in each group).The reference group was treated with atorvastatin+enalapril+valsartan.The observation group was combined with psychotherapy on the basis of the reference group.The clinical efficacy,HAMA score,HAMD score and patient satisfaction of the two groups were compared.Results The total clinical effective rate of the observation group(95.56%)was compared with that(91.11%)of the reference group(P>0.05).After treatment,the HAMA score and HAMD score of the observation group were lower than those of the reference group,and the patient satisfaction of the observation group(95.56%)was higher than that of the control group(73.33%).The difference was statistically significant(P<0.05).Conclusion Atorvastatin,enalapril and valsartan combined with psychotherapy can effectively improve the clinical symptoms and psychological state in patients with chronic nephritis.