针刺窍明穴为主配合常规取穴治疗原发性视网膜色素变性的临床疗效及对视野平均光敏感度和平均缺损的影响

Clinical Efficacy of acupuncture at Qiaoming point combined with common acupoints on retinitis pigmentosa and how to impact on mean sensitivity and mean defect of visual field

目的观察针刺窍明穴为主配合常规取穴治疗原发性视网膜色素变性(PRP)的临床疗效及对视野平均光敏感度(MS)和平均缺损(MD)的影响。方法将41例(82眼)PRP患者按照随机数字表法分为2组,对照组20例(40眼)予复方樟柳碱注射液、甲钴胺片治疗,对照组复方樟柳碱注射液治疗21 d为1个疗程,治疗2个疗程,疗程间隔7 d;甲钴胺片治疗2个月。治疗组21例(42眼)在对照组治疗基础上应用针刺窍明穴为主配合常规取穴治疗。治疗组治疗28 d为1个疗程,治疗2个疗程,疗程间隔2 d。比较2组视力、视野疗效;比较2组治疗前后30°视野平均光敏感度(MS)、平均缺损(MD)变化。结果治疗组视力总有效率85.7%(36/42)、视野总有效率71.4%(30/42),对照组视力总有效率62.5%(25/40)、视野总有效率47.5%(19/40),治疗组视力、视野疗效均优于对照组(P<0.05)。2组治疗后30°视野MS均较本组治疗前升高(P<0.05),MD均较本组治疗前降低(P<0.05),且治疗组治疗后30°视野MS均高于对照组(P<0.05),MD低于对照组(P<0.05)。结论针刺窍明穴为主配合常规取穴治疗PRP,能提高患者视力、视野疗效,升高30°视野MS,降低MD。

Objective To retrospectively analyze the clinical efficacy of acupuncture at Qiaoming point combined with common acupoints on retinitis pigmentosa(RP)and how to impact on mean sensitivity(MS)and mean defect(MD)of visual field.Methods A total of 41 patients(82 eyes)with primary RP were divided into the treatment group(21 cases,42 eyes)and the control group(20 cases,40 eyes).The control group was treated with compound anisodine injection and mecobalamin tablets,and the treatment group was treated with acupuncture at Qiaoming point combined with the routine acupoint selection based on the control group.Compound anisodine injection was used for 2 courses of treatment(21 days as a course of treatment,with an interval of 7 days),mecobalamin tablets was used for 2 months of treatment;the treatment group received 2 courses of treatment(28 days as a course of treatment,with an interval of 2 days);aiming to compare visual acuity and visual field efficacy,the changes of 30°MS and MD of visual field between groups before and after treatment.Results The overall effective rate of visual acuity and visual field was obviously better in the treatment group than the control group(85.7%[36/42]vs 62.5%[25/40],71.4%[30/42]vs 47.5%[19/40],[P<0.05],respectively).After treatment,the 30°MS of visual field in both groups was higher(P<0.05),which in treatment group was prevalent(P<0.05);MD in both groups was lower(P<0.05),the reduction in treatment group was more common(P<0.05).Conclusion For RP patients,acupuncture at Qiaoming point combined with conventional acupoint selection can improve the patient's visual acuity and visual field efficacy,elevate 30°MS of visual field,and reduce MD.