穴位埋线辅助治疗慢性阻塞性肺疾病的文献分析

Literature Analysis of Acupoint Catgut Embedding Therapy for Chronic Obstructive Pulmonary Disease

目的:评价穴位埋线治疗慢性阻塞性肺疾病的有效性和安全性。方法:通过登录中国知网、维普、万方及中国生物医学文献数据库等查阅文献资料,筛选穴位埋线治疗慢性阻塞性肺疾病的随机对照试验,治疗组为穴位埋线联合西医常规治疗,对照组单纯西医治疗,主要结局指标为临床有效率和急性加重次数,次要结局指标为肺功能、生存质量、6分钟步行距离、临床症状改善、不良反应及安全性指标,并采用RevMan 5.2软件进行数据分析。结果:将穴位埋线、常规西医治疗应用于临床中,与单纯西医治疗比较其临床有效率存在显著性优势,差异有统计学意义[RR=1.16,95%CI(1.07,1.27),P=0.0007],减少急性加重次数[MD=-0.54,95%CI(-0.91,-0.17),P=0.004],提高一秒用力呼气容积/用力肺活量[MD=5.30,95%CI(0.35,10.24),P=0.04],提高慢性阻塞性肺疾病评估测试表评分[MD=-2.12,95%CI(-3.50,-0.73),P=0.003],延长6分钟步行距离[MD=27.20,95%CI(17.55,36.84),P<0.00001],改善临床症状[MD=-1.25,95%CI(-1.37,-1.13),P=0.00001];而治疗组的一秒用力呼气容积及其占预计值的百分比与对照组比较差异无统计学意义。结论:西医常规治疗联合穴位埋线较单纯西医治疗能提高患者临床有效率,减少急性加重次数,改善肺功能,延长步行距离,显著缓解症状,提高生存质量,存在着较少的副反应,安全性较高,穴位埋线辅助治疗慢性阻塞性肺疾病具有显著疗效,因现有科学文献研究质量有待提高,今后还需通过更多随机对照试验来提供依据。

Objective:To evaluate the efficacy and safety of acupoint catgut embedding in the treatment of chronic obstructive pulmonary disease.Method:The randomized controlled trials of acupoint catgut embedding in the treatment of chronic obstructive pulmonary disease(COPD)were screened by logging into CNKI,VIP,Wanfang and China biomedical literature database.The treatment group was treated with acupoint catgut embedding combined with conventional western medicine,and the control group was treated with western medicine alone.The main outcome indicators were clinical effective rate and the number of acute exacerbations,and the secondary outcome indicators were lung function,quality of life,6-minute walking distance,improvement of clinical symptoms,adverse reactions and safety indicators.RevMan 5.2 software was used for data analysis.Results:The results showed that the clinical effective rate of acupoint catgut embedding and conventional western medicine treatment was significantly higher than that of Western medicine treatment alone,and the difference was statistically significant[RR=1.16,95%CI(1.07,1.27),P=0.0007],and the number of acute exacerbations was reduced[MD=-0.54,95%CI(-0.91,-0.17,P=0.004],increased forced expiratory volume in one second/forced vital capacity score[MD=5.30,95%CI(0.35,10.24),P=0.04],increased COPD assessment test score[MD=-2.12,95%CI(-3.50,-0.73),P=0.003],prolonged 6-minute walking distance[MD=27.20,95%CI(17.55,36.84),P<0.00001],and improved the clinical symptoms[MD=-1.25,95%CI(-1.37,-1.13),P=0.00001];but there was no significant difference in forced expiratory volume in one second and its percentage in the predicted value between the treatment group and the control group.Conclusion:Conventional western medicine combined with catgut embedding therapy can improve the clinical efficiency,reduce the number of acute exacerbations,improve lung function,extend walking distance,significantly relieve symptoms,improve the quality of life,with fewer side effects and higher safety.Acupoint catgut embedding has a significant effect in the treatment of chronic obstructive pulmonary disease.Because the quality of existing scientific literature needs to be improved,more randomized controlled trials are needed to provide the basis in the future.