吸附性血液滤过治疗脓毒症欧洲及亚太专家推荐意见解读

Interpretation of European and Asia Pacific expert recommendations on the use of adsorptive hemofiltration for sepsis

该文将欧洲和亚太地区专家分别于2019年和2021年发表的吸附性血液滤过用于脓毒症治疗的专家推荐意见要点进行对比解读,同时结合四川大学华西医院脓毒症血液净化的应用经验,从吸附性血液滤过治疗适用人群、实验室指标、治疗实施关键因素(包括启动时机、抗凝方式选择、停机时机判断等)等方面介绍了吸附性血液滤过治疗核心原则,可为临床治疗决策提供参考与借鉴。

After comparative interpretation of the essentials and highlights of the expert recommendations based on European experience published in 2019 and the expert recommendations based on Asia Pacific experience published in2021,this article summarizes the core principles of adsorptive hemofiltration for sepsis in following aspects,including patient selection,laboratory index,and key factors in the implementation of treatment(covering initiation timing and duration,choice of anticoagulant mode,discontinuation,etc)combined with the experience in West China Hospital of Sichuan University as well,to provide references for sepsis management with adsorptive hemofiltration in clinical practice.