支撑喉镜鼻内镜下低温等离子射频消融切除术治疗喉癌患者的效果

The effect of low-temperature plasma radiofrequency ablation under nasal endoscopy with supporting laryngoscope in the treatment of laryngocarcinoma

目的:探究支撑喉镜鼻内镜下低温等离子射频消融切除术治疗喉癌患者的效果。方法:选取103例早期声门型喉癌患者作为研究对象,采用信封法将其分为两组,对照组51例给予支撑喉镜下常规手术进行治疗,观察组52例给予支撑喉镜鼻内镜下低温等离子射频消融切除术治疗。对比两组临床疗效、围手术期相关指标、嗓音声学功能、呼吸功能。结果:术后,观察组的手术时间、术后住院时间、术中出血量、术后视觉模拟疼痛(VAS)评分、基频(F0)、基频微扰(Jitter)、振幅微扰(Shimmer)和标准化噪声能量(NNE)值低于对照组,临床疗效、黏膜恢复评分、谐噪比(HNR)、用力肺活量占预计值百分比(FVC%pred)、第1秒用力呼气容积占预计值百分比(FEV1%pred)、第1秒用力呼气容积占用力肺活量百分比(FEV1/FVC)、每分钟最大通气量占预计值百分比(MVV%pred)水平高于对照组(P<0.05)。结论:支撑喉镜鼻内镜下低温等离子射频消融切除术可以有效缩短喉癌患者的手术时间、住院时间,减少术中出血量,同时有效保护患者的嗓音声学功能和呼吸功能,减少术后疼痛,提高喉黏膜恢复效果。

Objective:This research aims to explore the effect of low-temperature plasma radiofrequency ablation under nasal endoscopy with supporting laryngoscope in the treatment of patients with laryngocarcinoma.Methods:103 patients with early glottic laryngocarcinoma were selected and divided into two groups by the envelope method.51 patients in the control group were given the conventional surgery under a supporting laryngoscope.52 patients in the observation group were treated with low-temperature plasma radiofrequency ablation under nasal endoscopy with supporting laryngoscopy.The clinical efficacy,perioperative indicators,voice acoustic function,and respiratory function of the two groups were compared.Results:After operation,the observation group′s operation time,postoperative hospital stay,intraoperative blood loss,postoperative visual analog scale(VAS)pain level,fundamental frequency(F0),fundamental frequency perturbation(Jitter),amplitude perturbation(Shimmer)and normalized noise energy(NNE)value are lower than those of the control group,and the clinical efficacy,total mucosal recovery score,harmonic noise ratio(HNR),percentage of forced vital capacity in predicted value(FVC%pred),percentage of forced expiratory volume in the first second in predicted value percentage(FEV1%pred),forced expiratory volume in the first second to forced vital capacity(FEV1/FVC),and percentage of maximum ventilation volume per minute in predicted value(MVV%pred)were higher than those of the control group(P<0.05).Conclusion:Low-temperature plasma radiofrequency ablation under nasal endoscopy with supportive laryngoscope can effectively shorten the operation time and hospital stay of patients with laryngocarcinoma,reduce intraoperative blood loss,effectively protect the patient’s voice acoustic function and respiratory function,and reduce postoperative pain,improve the recovery of laryngeal mucosa.