颅内动脉延长与扩张症的研究进展

Progress in the study of intracranial arterial dolichoectasia

颅内动脉延长与扩张症(IADE)亦称扩张性脑动脉病,表现为一支或者多支颅内动脉长度和直径增加,受累的动脉明显扩张延长,甚至蜿蜒迂曲。IADE的诊断和预后评估主要依据颅内动脉的直径及弯曲度。IADE可表现为缺血性脑卒中、短暂性脑缺血发作、脑积水、出血性卒中等。文中就IADE的概念、诊断标准、病因、发病机制、病理、临床表现、治疗及预后等方面进行综述。

Intracranial arterial dolichoectasia(IADE),also known as dilated cerebral artery disease,is manifested as an increase in the length and diameter of one or more intracranial arteries,the affected arteries being enlarged and dilated significantly,or even with winding and tortuosity.The diagnosis and prognostic evaluation of IADE are mainly based on the diameter and curvature of the intracranial artery.IADE can be manifested as ischemic stroke,transient ischemic attack,hydrocephalus,and hemorrhagic stroke.The review focuses on IADE,including the concept,diagnostic criteria,etiology,pathogenesis,pathology,clinical manifestations,treatment,and prognosis.