Nomogram for predicting disease-specific survival in osteosarcoma

To the Editor:Osteosarcoma(OS)is the most common malignant primary bone tumor majorly affecting children,adolescents,and young adults.Statistic studies showed that up to 20%of OS patients have clinically detectable metastatic tumor at presentation,and>85%of metastases occurs in the lung.Thus,identifying risk factors that reflect the biological characteristics and survival of OS could lead to better interventions for patients.