蜕膜巨噬细胞在复发性流产中的研究进展

Research advances of decidual macrophages in recurrent spontaneous abortion

复发性流产是临床难治性不育症, 其病因复杂, 近半数原因不明, 严重影响患者身心健康。蜕膜巨噬细胞在胚胎种植、胎盘形成及胎儿发育和分娩中发挥重要作用, 其数量、功能和表型与正常妊娠密切相关。本文就蜕膜巨噬细胞在复发性流产中的研究进展进行综述。

Recurrent spontaneous abortion is a clinical refractory infertility with complex etiology and nearly half of the causes are unexplained,which seriously affects the physical and mental health of patients.Decidual macrophages play an important role in embryo implantation,placenta formation,fetal development and delivery,and their number,function and phenotype are closely related to normal pregnancy.This article reviewed the research progress of decidual macrophages in recurrent spontaneous abortion.