大黄附子细辛汤灌肠治疗腹腔镜肝癌术后胃肠功能障碍的临床疗效

Effect of Dahuang Fuzi Xixin Decoction Enema on Gastrointestinal Dysfunction after Laparoscopic Hepatocellular Carcinoma

目的:观察大黄附子细辛汤中药灌肠治疗腹腔镜肝癌患者术后胃肠功能障碍的临床疗效。方法:选取2018年7月—2020年7月在广东省中医院肝胆外科行腹腔镜肝癌切除且术后出现胃肠功能障碍的患者102例,按随机数字表法分为治疗组和对照组,每组51例。两组患者均实施快速康复外科护理方案,对照组予以开塞露灌肠,治疗组予以大黄附子细辛汤灌肠,疗程为3 d,比较两组患者胃肠功能恢复情况,以及治疗前后腹胀评分。结果:治疗组肠鸣音恢复、首次肛门排气及首次排便时间均短于对照组,差异有统计学意义(P<0.05);治疗前,两组腹胀评分差异无统计学意义(P>0.05),治疗后,治疗组24 h、48 h腹胀评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗过程中,两组患者均未出现明显的不良反应。结论:大黄附子细辛汤灌肠治疗腹腔镜肝癌术后胃肠功能障碍的疗效显著,能快速促进腹腔镜肝癌术后患者胃肠功能恢复,且无不良反应,安全有效。

Objective To observe the clinical efficacy of Traditional Chinese medicine enema of Dahuang Fuzi Xixin Decoction on gastrointestinal dysfunction after laparoscopic hepatocellular carcinoma.Methods A total of 102 patients with postoperative gastrointestinal dysfunction who underwent laparoscopic hepatocellular carcinoma resection in the department of Hepatobiliary Surgery of Guangdong Province Traditional Medical hospital from July 2018 to July 2020 were selected and divided into treatment group and control group according to random number table method,with 51 patients in each group.Patients in both groups were given rapid rehabilitation surgical nursing program.The control group was given kaiselu enema and the treatment group was given Dahuang Fuzi Xixin Decoction enema.The course of treatment was 3 d,the gastrointestinal function recovery,abdominal distension score before and after treatment were compared between the two groups.Results The recovery time of bowel sound,first anal exhaust and first defecation in the treatment group were shorter than those in the control group(P<0.05).Before treatment,there was no significant difference in abdominal distension score between the two groups(P>0.05),but after treatment,the abdominal distension score of the treatment group at 24 h and 48 h was significantly lower than that of the control group(P<0.05).There were no obvious adverse reactions in two groups during treatment.Conclusion Dahuang Fuzi Xixin Decoction enema is effective in the treatment of gastrointestinal dysfunction after laparoscopic liver cancer surgery,which can quickly promote the recovery of gastrointestinal function of patients after laparoscopic hepatocellular carcinoma surgery,without adverse reactions,which is safe and effective.