气血舒颗粒质量控制研究

Quality Standard for Qixueshufu Granules

薄层色谱法对气血舒颗粒中人参外其余十味药进行定性鉴别,高效液相色谱法测定人参的主要活性成分人参皂苷Rg_(1)、Rb_(1)、Re含量。结果表明白芍、首乌藤、甘草、地黄、远志TLC鉴别专属性好;高效液相色谱建立的方法学可有效分离人参皂苷三种物质。本文通过定性和定量技术建立的药物标准体系简单,重复性好,可用于气血舒颗粒的质量控制标准。

TLC was used to qualitatively identify the other ten medicines in Qixueshu Granule except ginseng.The contents of ginsenoside Rg_(1),Rb_(1) and Re in Qixueshu Granule were determined by HPLC.TLC of Paeonia lactiflora,Polygonum multiflorum,glycyrrhiza,Rehmanniae and Polygala polygala was good.The method established by HPLC can effectively separate three kinds of ginsenosides.The drug standard system established by qualitative and quantitative techniques was simple and reproducible,which can be used for quality control of Qixueshu Granules.