摘要
目的:对中医古籍中治疗噎膈的专药进行挖掘并分析其用药规律,以探索现代食管癌相关中医临床研究。方法:挖掘《中华医典》数据库中治疗噎膈的专药,参考六本现行中药标准书籍对专药的性味归经和功效进行数据整理并进行数据分析。结果:共挖掘出符合入选标准的噎膈专药76种。药性以温、寒、平多见;药味以辛、甘、苦多见;归经以入脾、胃、肺、肝、肾经多见;药物功效以理气、止痛、解毒、补中、清热、温里、化痰多见。结论:食管癌病性可能为寒热胶结,病因可能包括气滞、痰湿、瘀血和热毒,病位可能涉及脾、胃、肺、肝、肾,处方用药可考虑以辛开、苦降、甘和为则。
Objective:To excavate the special medicines for the treatment of choking diaphragm in the ancient books of traditional Chinese medicine and analyze their medication rules,so as to explore the clinical research of modern Chinese medicine related to esophageal cancer.Methods:The special medicines for the treatment of choking diaphragm in the database of “Chinese Medical Dictionary” were excavated,and the data of the properties,taste,meridian and efficacy of special medicines were sorted and analyzed with reference to six current standard books of traditional Chinese medicine.Results:A total of 76 special drugs for choking diaphragm were excavated that met the inclusion criteria.The properties of medicine are mostly warm,cold and flat;the taste of medicine is mostly pungent,sweet and bitter;the meridian is more commonly used to enter the spleen,stomach,lung,liver and kidney meridians;the efficacy of medicine is to regulate Qi,relieve pain,detoxify,invigorate the middle and clear away heat,Wen Li,and phlegm are more common.Conclusion:The pathogenesis of esophageal cancer may be cold and heat cementation.The causes may include stagnation of Qi,phlegm-dampness,blood stasis and heat toxin.The disease location may involve the spleen,stomach,lung,liver and kidney.Prescription drugs can be considered with Xin Kai and Ku Jiang and Gan He is the rule.
作者
王若凡
孙亚云
张娟
WANG Ruofan;SUN Yayun;ZHANG Juan(Henan University of Chinese Medicine,Zhengzhou Henan 450046,China;The Second Affiliated Medical College of Henan University of Traditional Chinese Medicine,Zhengzhou Henan 450002,China;Zhumadian Hospital of traditional Chinese Medicine,Henan Zhumadian 463000,China)
出处
《中医药临床杂志》
2022年第7期1302-1306,共5页
Clinical Journal of Traditional Chinese Medicine
基金
国家中医临床研究基地科研专项(2019JDZX028,2019JDZX034,2019JDZX053)。
关键词
噎膈
食管癌
中医古籍
专病专药
用药规律
Choking diaphragm
Esophageal cancer
Ancient books of traditional Chinese medicine
Special medicine for special diseases
Medication rules