卒中后抑郁的筛查情况及相关影响因素研究

Screening of post-stroke depression and related influencing factors

目的了解卒中后抑郁的发病情况及相关影响因素。方法选取2019年4月-2019年10月在济南市第八人民医院住院的140例新发脑卒中患者为研究对象,登记一般资料信息。按汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)评分标准在患病2 w(A组)、3 m(B组)分别进行随访评分了解患病情况,并对相关影响因素进行统计学分析。结果A组、B组PSD发病率分别为25.7%(36/140)、40.3%(48/119),均以轻中度抑郁为主。女性、无稳定工作者、文化程度高者、左半球病灶者、多病灶者、复发患者、糖尿病患者及烟酒不良嗜好者有PSD高发趋势,但差异无统计学意义(P>0.05);月均可支配医疗费用500元以下者、改良Barthel评分低者发病率高,差异有统计学意义(P<0.05)。结论卒中后抑郁发病率较高,发病人群及发病率随时间变化,女性、无稳定工作者、文化程度高者、左半球病灶者、多病灶者、复发患者、糖尿病患者及烟酒不良嗜好者存在PSD高发趋势;月均可支配医疗费用500元以下者、日常生活活动能力低者是PSD的重要患病因素。

Objective To investigate the incidence and related factors of post-stroke depression.Method 140 new stroke patients admitted to The Eighth People’s Hospital of Jinan City from April 2019 to October 2019 were selected as the research objects,and the general information was registered.The patients were followed up at 2 weeks(group A)、3 months(group B)according to Hamilton Depression Scale(HAMD)in order to understand the prevalence,and the related factors were statistically analyzed.Result The incidence rate of PSD in group A and group B was 25.7%(36/140)and 40.3%(48/119)respectively,all of them were mainly mild to moderate depression.Female,no stable workers,high education level,left hemisphere lesions,multiple lesions,relapsed patients,diabetes patients and bad habit of smoking and drinking had a high incidence of PSD,but the difference was not statistically significant(P>0.05).Those with a monthly medical expenditure of less than 500 yuan and a lower Barthel score had a higher incidence rate,and the difference was statistically significant(P<0.05).Conclusion The incidence rate of post stroke depression is high,the sick crowd and incidence rate are varied with time.Women,unstable workers,high education level,left hemisphere lesions,multifocal disease,relapse,diabetes and patients with bad habit of smoking and drinking have high incidence trend of PSD.Those with monthly disposable medical expenses less than 500 yuan and low activities of daily living were the important risk factors of PSD.