摘要
为了高效、高收率地获得新型N-苯磺酰基苯乙酰胺脱落酸类似物,取代苯乙炔和苯磺酰叠氮为起始原料,水相中超声辐射下经廉价的CuSO_(4)/NaAsc(NaAsc为抗坏血酸钠)催化获得32个目标化合物.该方法操作简单、收率高(86%~95%)、溶剂环保.种子萌发实验结果表明,25和50μmol/L目标化合物处理后大豆种子发芽明显受阻,其中22个目标化合物处理后抑制率为100%,活性优于脱落酸(ABA).该结果有利于快速地合成具有高抑制萌发活性的新型脱落酸类似物。
Substituted phenylene and benzenesulfonyl-azides were used as starting materials to obtain N-benzensulfonyl phenylacetamide abscisic mimics(PACs).32 target compounds were efficiently and quickly obtained via cheap combination of CuSO_(4)/NaAsc(NaAsc,sodium ascorbate)catalysis under ultrasonic radiation in water(86%~95%).Furthermore,22 target compounds could overwhelmingly inhibit soybean seed germination at the concentration of 50 and 25μml/L.These results are benefit to discovering novel seed germination inhibitor agents.
作者
黄志友
李哲陟
何波
李文胜
杨平
陈立军
Huang Zhiyou;Li Zhezhi;He Bo;Li Wensheng;Yang Ping;Chen Lijun(a College of Urban and Rural Construction,Shaoyang University,Shaoyang,Hunan 422000;Key Laboratory of Integrated Management of Crop Disease and Pests,Ministry of Education,Nanjing Agricultural University,Nanjing,Hunan 210095;Shaoyang City Sixteen Middle School,Shaoyang University,Shaoyang,Hunan 422000)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2022年第6期1667-1676,共10页
Chinese Journal of Organic Chemistry
基金
湖南省自然科学基金青年项目(No.2021JJ40515)
湖南省教育厅科学研究(No.21B0677)资助项目.
