催产素在瘢痕子宫妊娠产妇中的应用效果与安全性

Application Effect and Safety of Oxytocin in Pregnant Women with Scar Uterus

目的:探讨催产素在瘢痕子宫妊娠产妇中的应用效果与安全性。方法:选取2020年1月-2021年6月高州市中医院进行分娩的90例瘢痕子宫妊娠产妇为研究对象。按照随机数字表法将其分为对照组(n=45)和观察组(n=45)。对照组给予常规分娩管理干预,在此基础上,观察组予以静脉滴注催产素,采用缩宫素注射液干预。比较两组分娩方式、产程时间、宫颈成熟度、新生儿5 min Apgar评分和产后出血量、不良母婴结局。结果:观察组阴道分娩率高于对照组,中转剖宫产率低于对照组(P<0.05)。观察组第一产程、第二产程、第三产程及总产程时间均短于对照组(P<0.05)。临产时,观察组产妇Bishop评分高于对照组,产后出血量少于对照组(P<0.05)。两组新生儿5 min Apgar评分比较差异无统计学意义(P>0.05)。两组不良母婴结局发生率比较差异无统计学意义(P>0.05)。结论:催产素可提高瘢痕子宫妊娠产妇阴道分娩率,促进宫颈成熟,缩短产程时间,且不会增加不良母婴结局的发生风险。

Objective:To explore the application effect and safety of oxytocin in pregnant women with scar uterus.Method:A total of 90 pregnant women with scar uterus who delivered in Gaozhou Hospital of Traditional Chinese Medicine from January 2020 to June 2021 were selected as the research objects.They were divided into control group(n=45)and observation group(n=45)according to the random number table method.The control group was given routine delivery management intervention.On this basis,the observation group was given intravenous drip Oxytocin and Oxytocin Injection intervention was used.The mode of delivery,duration of labor,cervical maturity,neonatal 5 min Apgar score,postpartum hemorrhage volume and adverse maternal and infant outcomes were compared between the two groups.Result:The vaginal delivery rate in the observation group was higher than that in the control group,and the rate of conversion to cesarean section was lower than that in the control group(P<0.05).The first stage of labor,the second stage of labor,the third stage of labor and the total stage of labor in the observation group were shorter than those in the control group(P<0.05).After delivery,the Bishop score of the observation group was higher than that of the control group,and the postpartum hemorrhage volume was less than that of the control group(P<0.05).There was no significant difference in neonatal 5 min Apgar score between the two groups(P>0.05).There was no significant difference in the incidence of adverse maternal and infant outcomes between the two groups(P>0.05).Conclusion:Oxytocin can improve the vaginal delivery rate of pregnant women with scar uterus,promote the cervical maturity,shorten the time of labor,and will not increase the occurence risk of adverse maternal and infant outcomes.