摘要
BACKGROUND Health utility assessments have been developed for various conditions,including chronic liver disease.Health utility scores are required for socio-economic evaluations,which can aid the distribution of national budgets.However,the standard health utility assessment scores for specific health conditions are largely unknown.AIM To summarize the health utility scores,including the EuroQOL 5-dimensions 5-levels(EQ-5D-5L),EuroQol-visual analogue scale,short from-36(SF-36),RAND-36,and Health Utilities Index(HUI)-Mark2/Mark3 scores,for the normal population and chronic liver disease patients.METHODS A systematic literature search of PubMed and MEDLINE,including the Cochrane Library,was performed.Meta-analysis was performed using the RevMan software.Multiple means and standard deviations were combined using the StatsToDo online web program.RESULTS The EQ-5D-5L and SF-36 can be used for health utility evaluations during antiviral therapy for hepatitis C.HUI-Mark2/Mark3 indicated that the health utility scores of hepatitis B patients are roughly 30% better than those of hepatitis C patients.CONCLUSION The EQ-5D-5L is the most popular questionnaire for health utility assessments.Health assessments that allow free registration would be useful for evaluating health utility in patients with liver disease.
基金
Supported by Grants-in-Aid from JSPS KAKENHI,No.JP 20K10404(to Mizuguchi T)and No.JP 21K10715(to Ishinuki T)
the Hokkaido Hepatitis B Litigation Orange Fund,No.2059198(to Mizuguchi T)and No.2136589(to Harada K)
Terumo Life Science Foundation,No.2000666
Pfizer Health Research Foundation,No.2000777
the Viral Hepatitis Research Foundation of Japan,No.3039838
Project Mirai Cancer Research Grants,No.202110251
Takahashi Industrial and Economic Research Foundation,No.12-003-106
Daiichi Sankyo Company,No.2109540
Shionogi and Co.,No.2109493
MSD,No.2099412
Takeda Pharmaceutical Company,No.2000555
Sapporo Doto Hospital,No.2039118
Noguchi Hospital,No.2029083
Doki-kai Tomakomai Hospital,No.2059203
Tsuchida Hospital,No.2000092
Shinyu-kai Noguchi Hospital,No.2029083(to Mizuguchi T)
the Yasuda Medical Foundation,No.28-1(to Ishinuki T).
