琥珀酸亚铁与蚕砂提取物治疗缺铁性贫血孕妇的效果及不良反应对比

Comparison on the Effects and Adverse Reactions of Ferrous Succinate and Silkworm Sand Extract in the Treatment of Pregnant Women with Iron Deficiency Anemia

目的 比较琥珀酸亚铁与蚕砂提取物治疗缺铁性贫血孕妇的效果及不良反应。方法 134例缺血性贫血孕妇随机分为两组,观察组采用琥珀酸亚铁治疗,对照组采用生血宁片治疗,比较两组的疗效、血液指标及不良反应。结果 治疗后,观察组的总有效率、不良反应发生率,以及血红蛋白、红细胞计数、血清铁蛋白水平均高于对照组(P <0.05)。结论 与蚕砂提取物相比,琥珀酸亚铁治疗缺铁性贫血孕妇的效果更显著,但不良反应发生率较高;对于出现不良反应的孕妇可采取蚕砂提取物缓慢补铁。

Objective To compare the effects and adverse reactions of ferrous succinate and silkworm sand extract in the treatment of pregnant women with iron deficiency anemia.Methods 134 pregnant women with iron deficiency anemia were randomly divided into two groups.The observation group was treated with ferrous succinate,and the control group was treated with Shengxuening tablets.The efficacy,blood indicators and adverse reactions were compared between the two groups.Results After treatment,the total effective rate and incidence of adverse reactions,and the levels of hemoglobin,red blood cell count and serum ferritin were higher than those in the control group(P <0.05).Conclusions Compared with silkworm sand extract,ferrous succinate has more significant effect in the treatment of pregnant women with iron deficiency anemia,while the incidence of adverse reactions is higher;For pregnant women with adverse reactions,silkworm sand extract can be used to slowly supplement iron.