集束化消毒干预措施降低呼吸机相关肺炎发病率的研究

Study on reducing the incidence of ventilator-associated pneumonia by disinfection bundles intervention

目的研究集束化消毒干预措施对接受有创机械通气患者呼吸机相关肺炎(VAP)发病率的影响。方法通过VAP病例监测方法,对集束化消毒干预措施降低接受有创机械通气住院患者VAP发病率的效果进行观察。结果集束化消毒干预措施实施后,呼吸机进气口、呼气盒内表面、模拟肺使用后接口处、模拟肺使用前(消毒后)内表面、模拟肺使用后内表面的带菌率均显著下降,差异具有统计学意义(P<0.05)。集束化消毒干预措施组患者的VAP发病率为7.2%,略低于实施单一措施的对照组(10.4%)。结论采用基于“预防外源性交叉感染”的集束化消毒干预,可以减少交叉感染,降低有创机械通气患者VAP发病率。

Objective To study the effect of disinfection bundles intervention on the incidence of ventilator-associated pneumonia(VAP)in patients with invasive mechanical ventilation.Methods The effect of disinfection bundles intervention on reducing the incidence of VAP in hospitalized patients undergoing invasive mechanical ventilation was observed by means of VAP case monitoring.Results After the implementation of the disinfection bundles intervention,the bacteria-holding rate of the ventilator air inlet,the inner surface of the exhalation box,the interface of the simulated lung after use,the inner surface of the simulated lung before use(after disinfection),and the inner surface of the simulated lung after use were all significantly decreased,and the difference was statistically significant(P<0.05).Disinfection bundles intervention could reduce the incidence of VAP(7.2%),but the difference was not statistically significant(P>0.05).Conclusion The disinfection bundles intervention based on“prevention of exogenous cross-infection”can reduce cross-infection and the incidence of VAP in patients with invasive mechanical ventilation.