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A need for stratification of metastasis samples according to secondary site in gene expression studies

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摘要 Comparisons of gene expression profiles between primary tumors and metastasis have revealed genes that are implicated in metastasis formation.However,gene expression studies conducted on metastasis samples from the same primary site usually do not discriminate between different secondary sites.Although the change in the expression of number of genes is expected to be common to metastasis from the same primary but different secondary sites,herein the data that point to substantial differences are presented.Furthermore,the reciprocal communication between metastatic and host cells that is influencing these differences is outlined to emphasize the need for stratification of metastasis samples in gene expression studies.
出处 《BIOCELL》 SCIE 2022年第7期1747-1750,共4页 生物细胞(英文)
基金 This work was supported by MY ZABA START 2019 donation from Zagrebačka banka:https://www.zaba.hr/home/en/about-us/community-involvement/my-zabastart The funder had no role in study design,data collection,analysis,and interpretation,decision to publish,or preparation of the manuscript.
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