阿替普酶联合丁苯酞治疗急性脑梗死患者的效果

Effect of Atteplase Combined with Buphthalein on Acute Cerebral Infarction

目的分析急性脑梗死患者应用阿替普酶联合丁苯酞治疗的效果。方法此次研究将本院收治的急性脑梗死患者作为研究对象,患者入院时间均在2019年2月至2020年2月,共58例。按照随机数表法分成治疗A组及治疗B组。其中治疗A组采取单纯丁苯酞治疗,治疗B组则采取阿替普酶联合丁苯酞治疗,各29例。治疗后对其治疗有效率、NIHSS评分、MoCA评分、血清学指标、应激炎性因子水平以及治疗满意度情况进行比较分析。结果治疗后,于治疗有效率方面,治疗A组显著低于治疗B组(P<0.05)。于NIHSS评分、MoCA评分方面,治疗前,两组数据对比差异无统计学意义(P>0.05),治疗后,治疗A组显著低于治疗B组(P<0.05)。于血清学指标、应激炎性因子水平方面,治疗前,两组数据对比差异无统计学意义(P>0.05),治疗后,治疗A组显著低于治疗B组(P<0.05)。于治疗满意度方面,治疗A组显著低于治疗B组(P<0.05)。结论在急性脑梗死患者的治疗中采取阿替普酶联合丁苯酞治疗的效果显著,能够对患者的治疗有效率予以提升,并对其神经功能缺损以及认知能力进行较好的改善,还可改善其血清学指标以及应激炎性因子水平,从而对患者的治疗满意度大幅度提升。

Objective To analyze the effect of alteplase combined with terephthalein treatment in patients with acute cerebral infarction.Methods Patients with acute cerebral infarction admitted to this hospital were taken as the subjects in this study,and 58 patients were admitted from February 2019 to February 2020.They were divided into treatment group A and treatment group B according to the randomized number table method.In group A,buphthalein alone was treated,and in group B,attepase combined with buphthalein was treated,with 29 from each of the above two groups.Comparative analysis of their treatment efficiency,NIHSS score,MoCA score,serum indicators,levels of stress inflammatory factors,and treatment satisfaction after treatment.Results After treatment,treatment group A was significantly lower than treatment group B(P<0.05).As seen in the NIHSS score and MoCA score,the difference in data comparison between treatment groups A and B did not meet the statistical significance(P>0.05),and after treatment,treatment A group was worse than treatment group B(P<0.05).As seen in serum indicators and levels of stress inflammatory factors,the difference in data between treatment A and B did not meet the statistical significance(P>0.05)before treatment,and after treatment,treatment A was significantly worse than treatment B(P<0.05).In treatment satisfaction,treatment A was lower than in treatment B(P<0.05).Conclusion In the treatment of acute cerebral infarction patients with the treatment effect is outstanding,this combination treatment can improve the efficiency of patients,and its neurological defects and cognitive ability,can improve its serum indicators and stress inflammatory factors level,so as to improve the satisfaction with treatment of patients.