介入治疗急性ST段抬高型心肌梗死的远期疗效探析

Analysis on the Long-term Effect of Interventional Therapy for Acute ST Segment Elevation Myocardial Infarction

目的探析介入治疗急性ST段抬高型心肌梗死的远期疗效。方法随机选取2018年1月至2019年12月本院收治的80例急性ST段抬高型心肌梗死患者,按照随机数字表法分为常规组与观察组。常规组40例实施常规治疗;观察组40例在常规治疗的基础上实施介入治疗。对比两组患者的胸部疼痛消失率、心功能显著改善率、心电图ST段的显著改善率、心功能指标、脑钠肽变化情况、并发症发生情况以及心血管事件发生情况。结果治疗后,观察组胸部疼痛消失率、心功能显著改善率、心电图ST段显著改善率均明显高于常规组(P<0.05);观察组患者的左室射血分数(LVEF)高于常规组,观察组患者的左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)低于常规组(P<0.05);治疗后,两组患者的血浆脑钠肽(BNP)水平明显低于治疗前,且观察组低于常规组(P<0.05);观察组并发症发生率低于常规组(2.50%vs.20.00%),组间差异显著(P<0.05);术后白细胞、NLR水平均较低,呈现递减趋势,且逐步趋于正常状态。特别是在术后7 d、12 d与术前对比,指标差异显著(P<0.05),术后1 d患者血清CRP与术前比较显著提高,P<0.05。结论急性ST段抬高型心肌梗死患者实施介入治疗,能够有效改善患者心功能,降低脑钠肽水平,减少并发症以及心血管时间发生率,疾病远期疗效良好。

Objective To explore the long-term efficacy of interventional therapy for acute ST segment elevation myocardial infarction.Methods 80 patients with acute ST segment elevation myocardial infarction treated in our hospital from january 2018 to december 2019 were randomly selected.the random digital table method was divided into routine group and observation group.The routine group of 40 cases,the implementation of routine treatment;the observation group of 40 cases,on the basis of routine treatment to implement interventional therapy.Comparison of chest pain loss rate,cardiac function improvement rate,electrocardiogram ST segment improvement rate,cardiac function index,brain natriuretic peptide changes,complications and cardiovascular events in the two groups.Results After treatment,the disappearance rate of chest pain,the significant improvement rate of cardiac function,and the significant improvement rate of ECG ST segment in the observation group were significantly higher than those in the routine group(P<0.05).The left ventricular ejection fraction(LVEF)of the observation group was higher than that of the routine group,the left ventricular end-diastolic volume(LVEDV)and left ventricular end-systolic volume(LVESV)of the observation group were lower than those of the routine group(P<0.05).After treatment,the plasma brain natriuretic peptide(BNP)levels of the two groups were significantly lower than before treatment,and the observation group was lower than the routine group(P<0.05).The incidence of complications in the observation group was lower than that in the routine group(2.50%vs.20.00%),and the difference between the groups was significant(P<0.05).Postoperative leukocyte and NLR levels were low,showing a decreasing trend,and gradually tended to normal state.Especially at 7 days and 12 days after operation,compared with preoperative,there were significant differences(P<0.05).The serum CRP of patients on postoperative 1 days was significantly higher than that before operation,P<0.05.Conclusion Interventional therapy in patients with acute ST elevation myocardial infarction can effectively improve cardiac function,reduce brain natriuretic peptide level,reduce complications and cardiovascular time incidence,and the long-term effect of the disease is good.