黄斑区神经节细胞复合体厚度形态特征在视路相关神经眼科的定位诊断价值

The location diagnostic value of morphologic features of macular ganglion cell complex thickness in optic pathway-related neuro-ophthalmology

采用扫频光学相干断层扫描仪(SS‑OCT)的黄斑区神经节细胞复合体(mGCC)厚度形态特征分析视路相关神经眼科疾病,mGCC具有类似视野的定位诊断价值,黄斑区神经节细胞分布具有精准的水平、垂直及象限性规律特征,具体表现为:视交叉前病变表现为单眼mGCC环萎缩变薄或者水平划界上下半侧mGCC萎缩、视交叉部病变表现为中垂线划界双眼鼻侧半mGCC萎缩变薄、视交叉后视路病变表现为中垂线划界同向半侧或1/4象限mGCC萎缩。mGCC厚度形态特征在视路相关神经眼科疾病的诊治中具有客观定位分析的价值。

The current study analyzed the morphologic features of macular ganglion cell complex(mGCC)thickness in optic pathway-related neuro-ophthalmic diseases by swept-source optical coherence tomography(SS-OCT).mGCC has the location diagnostic value similar to visual field,and the distribution of macular ganglion cells has accurate horizontal,vertical and quadrant characteristics.Specifically,prechiasmatic lesions showed atrophy and thinning of mGCC ring in single eye or mGCC atrophy in the upper and lower half of horizontal demarcation,chiasmatic lesions exhibited atrophy and thinning of mGCC in the half of bilateral nasal side demarcated by mid-vertical line,and retrochiasmatic lesions presented with atrophy of mGCC in the half of mid-vertical line demarcated or 1/4 quadrant.Therefore,the morphological characteristics of mGCC thickness are of value in the location diagnosis of optic path-related neuro-ophthalmic diseases.