摘要
The epidermal cell differentiation regulator zinc finger protein 750(ZNF750)is a transcription factor containing the Cys2His2(C2H2)domain,the zinc finger structure of which is located at the N-terminal 25-46 amino acids of ZNF750.It can promote the expression of differentiation-related factors while in-hibiting the expression of progenitor cell-related genes.ZNF750 is directly regulated by p63(encoded by the TP63 gene,belonging to the TP53 superfamily).
基金
This work was supported by the National Natural Science Foundation of China(No.81802268)
the Fujian Provincial Department of Science and Technology(Nos.2020J05298 and 2021J011364)
the Fujian Province Health and Family Planning(No.2019-CXB-30)
the Xiamen City Department of Health(No.3502Z20214ZD1006),China.
