期刊文献+

脑专用PET显像探测器自由结构符合与初步实验测试

Coincidence of Free Structure and Preliminary Experimental Testing of a Specialized Brain PET Imaging Detector
下载PDF
导出
摘要 采用脑PET进行人脑功能的研究对生物医学起到至关重要的作用,为了显著提高脑PET显像质量,增加探测效率、实时显示图像,本文设计一种脑专用PET显像大面积平板型探测系统,该探测系统由两个大面积探头组成,每个大面积探头包含3×3阵列的位置灵敏光电倍增管和多个紧密排布的硅酸钇镥闪烁晶体(Ce:LYSO)阵列。并利用1μCi的^(22)Na点源对晶格大小为0.7 mm×0.7 mm等六种LYSO晶体阵列进行晶体性能测试,并选用两块晶格大小为1.5 mm×1.5 mm的LYSO晶体阵列进行一对一符合探测初步断层显像。结果显示,各种晶格大小的LYSO晶体阵列的位置区分轮廓的半高宽平均值在0.38~0.49 mm之间,平均能量分辨率(半高宽)在17.61%~30.40%之间;在对^(22)Na点源的初步图像断层扫描实验测试中,通过滤波反投影算法获得重建图像的空间分辨率为1.5 mm,验证了大面积平板型探测系统的可行性。 Brain positron emission tomography(PET)plays an important role in the study of human brain function for biomedical.In order to significantly improve the quality of brain PET imaging,increase detection efficiency,and display images in real time,a specialized large-area panel detection system for brain PET imaging is designed,and preliminary experimental tests are carried out for this design.The PET detection system consists of two large-area probes,each containing a 3×3 array of position-sensitive photomultiplier tubes and multiple tightly arranged array-type Cerium and Yttrium Doped Lutetium Oxyorthosilicate(Ce:LYSO)scintillation crystals.A ^(22)Na point source with 1μCi was used to test the crystal properties of LYSO crystal arrays with pixels sized from 0.7 mm×0.7 mm to 2.0 mm×2.0 mm.And two LYSO crystal arrays with pixels of 1.5 mm×1.5 mm were selected for preliminary tomography of one-to-one coincidence detection.The experimental results show that the average FWHMs of position discriminating profiles of LYSO crystal arrays with various pixels are between 0.38 mm and 0.49 mm,and the average values of energy resolution(FWHM)are between 20%and 30%.In the initial image tomography test of ^(22)Na point source,the resolution of reconstructed image is obtained as 1.5 mm by filtering back projection algorithm,which verifies the feasibility of large-area panel detection system.
作者 文婧 李英帼 黄川 张庆华 裴昌旭 何丽霞 尹永智 WEN Jing;LI Yingguo;HUANG Chuan;ZHANG Qinghua;PEI Changxu;HE Lixia;YIN Yongzhi(School of Nuclear Science and Technology,Lanzhou University,Lanzhou 730000,China;China Institute of Atomic Energy,Beijing 102413,China)
出处 《同位素》 CAS 2022年第4期233-241,I0001,共10页 Journal of Isotopes
基金 国家自然科学基金面上项目(11875156) 兰州大学中央高校基本科研业务费专项资金资助(lzujbky-2021-ct02)。
关键词 脑PET 大面积探测器 能量分辨率 二维位置分布图 图像重建 brain PET large-area detector energy resolution 2D position distribution map image reconstruction
  • 相关文献

参考文献1

共引文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部