马来酸麦角新碱预防宫缩乏力性产后出血的临床效果

Clinical effect of Ergometrine Maleate in preventing postpartum hemorrhage caused by uterine atony

目的观察马来酸麦角新碱预防宫缩乏力性产后出血的临床效果。方法选取2021年1月至2022年2月于淄博市高青县妇幼保健院建档产检且自然分娩的86例产妇,采用随机数字表法分为对照组和观察组,每组各43例。对照组产后常规应用缩宫素治疗,观察组产后在常规缩宫素应用基础上给予马来酸麦角新碱治疗,观察两组产妇产后不同时间出血量、宫底高度,观察并比较两组用药期间安全性。结果观察组产妇产后2、24和48 h出血量低于对照组,差异有统计学意义(P<0.05)。两组产妇产后1 d宫底高度比较,差异无统计学意义(P>0.05);产后3 d观察组产妇宫底高度低于对照组(P<0.05)。观察组产妇用药不良反应总发生率高于对照组,但差异无统计学意义(11.63%vs.6.98%,P>0.05)。结论马来酸麦角新碱预防阴道分娩产后出血效果显著,可提高产妇子宫复旧速度,安全可靠。

Objective To observe the clinical effect of Ergometrine Maleate in preventing postpartum hemorrhage caused by uterine atony.Methods A total of 86 puerpera who were registered for prenatal care and gave birth spontaneously in the Maternal and Child Health Hospital of Gaoqing County in Zibo City from January 2021 to February 2022 were selected and divided into the control group and the observation group by random number table method,43 cases in each group.The control group was given routine postpartum Oxytocin treatment,the observation group was given Ergometrine Maleate on the basis of routine Oxytocin after delivery.The postpartum hemorrhage volume and fundus height of the two groups were observed at different time,and the safety during the medication was observed and compared between the two groups.Results The bleeding volume at 2,24 and 48 h after delivery of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in fundal height between the two groups at 1 d after delivery(P>0.05).The fundus height at 3 d after delivery in the observation group was lower than that in the control group(P<0.05).The total incidence of adverse drug reactions in the observation group was higher than that in the control group,but the difference was not statistically significant(11.63%vs.6.98%,P>0.05).Conclusion Ergometrine Maleate has a significant effect on preventing postpartum hemorrhage after vaginal delivery,and can improve t he speed of uterine involution,which is safe and reliable.