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液氮制粒冻干工艺及生产线设计探讨

Study on Lyophilization Technology and Production Line Design of Liquid Nitrogen Granulation
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摘要 液氮制粒冻干技术对冻干产品质量有着重要提升作用。通过大量的实验分析总结出液氮制粒冻干在缩短冻干周期、保持生物活性和方便出料等方面具有明显优势,并进一步根据产品工艺特点总结了该技术的生产工艺开发的要点。通过本文的分析为冻干产品的生产模式提供新的选择方案。 Lyophilization technology of liquid nitrogen granulation plays an important role in improving the quality of lyophilized products.In the paper,Through a large number of experimental analysis,it was concluded that lyophilization of liquid nitrogen granulation had obvious advantages in shortening lyophilization cycle,maintaining biological activity and convenient discharging,and further summarized the key points of production process development of this technology according to the product process characteristics.The analysis of this paper provided a new selection scheme for the production mode of lyophilized products.
作者 王春峰 Wang Chunfeng(Tofflon Science and Technology Group Co.,Ltd,Shanghai 201108,China)
出处 《化工与医药工程》 2022年第4期61-64,共4页 Chemical and Pharmaceutical Engineering
关键词 冻干 液氮制粒 生物活性 液氮 lyophilization liquid nitrogen granulation biological activity liquid nitrogen
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