1374例儿童呼吸道病原体检测结果分析

Analysis of IgM of pathogens of respiratory tract infection in 1374 cases

目的:分析东营地区患儿常见呼吸道感染的病原体免疫球蛋白M(IgM)抗体及其感染特点。方法:采用间接免疫荧光法检测东营市立儿童医院2018年1月-2021年2月1374例呼吸道感染住院患儿血清中呼吸道8项病原体IgM抗体。结果:350例标本IgM抗体检测阳性,其中肺炎支原体(MP)的阳性率最高,为8.08%;双重感染主要为MP合并一乙型流感病毒(FluB)感染。男性患儿呼吸道病原体IgM抗体阳性率(22.47%)显著低于女性患儿(29.55%)。各年龄组(0~1岁、1~3岁、4~6岁、6~14岁)的检出率分别为10.28%、38.27%、35.56%、36.84%,各组间差异有统计学意义(P<0.05)。春季总的病原体感染率最高,其次是夏季、再次是冬季和秋季。结论:呼吸道病原体的感染率与性别、季节、年龄段相关,对于我们针对性的防范具有重要的临床意义。

Objective:To detect the IgM antibodies and epidemiology of pathogens of respiratory tract infection in children of Dongying area.Methods:The serum of 1374 patient cases in Dongying Children7 s Hospital from January 2018 to February 2021 were detected by indirect immunofluorescence.Results:Totally 350 specimens were positive for IgM antibody detection and the positive rate of MP with 8.08%was highest;Double infection is mainly MP complicated with Flu B infection.The positive rate of IgM antibody against respiratory pathogens in male children(22.47%)was significantly lower than that in female children(29.55%).The detection rates of all age groups(0-1y,1-3y,4-6y and 6-14y) were 1028%,3827%,35.56%and 36.84%respectively.There was significant difierence among the groups(P<0.05).The total pathogen infection rate was the highest in spring,followed by summer,winter and autumn.Con elusion:The infection rate of respiratory pathogens is related to gender,season and age,so it is of great clinical significance to take preventive measures.