替罗非班对急性脑梗死的治疗应用进展分析

Progress of Application of Tirofiban in the Treatment of Acute Cerebral Infarction

急性脑梗死(AMI)的主要发生原因为冠状动脉粥样硬化,及血小板粘附和聚集、斑块出现破裂等,其发病率呈逐年上升的趋势。AMI属于伴有冠状动脉急性的闭塞,为临床方面的综合征。现阶段,一般采取抑制拮抗血小板的粘附情况,及抑制聚集反应的方式治疗本病,以降低血栓的形成。临床实践证明,在急性脑梗死治疗中应用替罗非班,对疾病具有非常良好的治疗效果。替罗非班是常见的受体抑制剂,可以对血小板聚集现象起到阻断作用,有效防止血栓形成。急性脑梗死发生后,血栓形成会危急患者生命安全,而使用替罗非班则可以有效控制疾病的发展速度,防止血栓形成,恢复患者的神经功能,同时能够降低致残率和死亡风险,在极大程度上保障患者的生命安全。本文首先阐述急性脑梗死的发病机制和替罗非班的药理作用机制,最后分析替罗非班在急性脑梗死治疗中的应用情况。

Acute cerebral infarction(AMI)is mainly caused by coronary atherosclerosis,as well as platelet adhesion and aggregation and plaque rupture,and its incidence is increasing year by year.At this stage,the treatment of these conditions is usually carried out by inhibiting the antagonistic platelet adhesion situation and inhibiting the aggregation reaction to reduce the formation of blood clots.Clinical practice has proved that the application of tirofiban in the treatment of acute cerebral infarction has a very good effect on the treatment of the disease.Tirofiban is a common receptor inhibitor,which can have a blocking effect on platelet aggregation phenomenon and effectively prevent thrombosis.The use of tirofiban can effectively control the development of the disease,prevent the formation of thrombus,restore the neurological function of patients,and reduce the risk of disability and death,which can protect the life of patients to a great extent.This paper firstly describes the pathogenesis of acute cerebral infarction and the pharmacological mechanism of action of tirofiban,and finally analyzes the application of tirofiban in the treatment of acute cerebral infarction.