自拟健脾补肺方治疗肺脾气虚型小儿哮喘临床观察

Clinical Observation on Strengthening Spleen and Supplementing Lung Prescription in the Treatment of Infantile Asthma of Qi Deficiency of Lung and Spleen Type

目的观察自拟健脾补肺方治疗小儿哮喘肺脾气虚证的临床效果。方法选取上海市浦东新区光明中医医院2018年1月—2019年7月120例儿科门诊肺脾气虚型哮喘患儿,按照随机数字表法分为参照组和观察组,每组60例。参照组给予口服孟鲁司特钠治疗,观察组采用自拟健脾补肺方治疗。比较2组患儿的临床疗效、不良反应发生情况、复发率及治疗前后临床症状积分变化情况。结果2组患儿治疗后临床症状积分低于治疗前,且观察组低于参照组,差异有统计学意义(P<0.05)。观察组总有效率为90.00%(54/60),参照组总有效率为71.67%(43/60),2组患儿总有效率比较,差异有统计学意义(P<0.05)。参照组复发率48.33%(29/60),观察组复发率21.67%(13/60),2组患儿复发率比较,差异有统计学意义(P<0.05)。结论自拟健脾补肺方可改善肺脾气虚型哮喘患儿的临床症状,降低复发率。

Objective To observe the clinical effect of strengthening spleen and supplementing lung prescription in the treatment of infantile asthma of syndrome of qi deficiency of lung and spleen.Methods 120 cases of infantile asthma of syndrome of qi deficiency of lung and spleen patients in Guangming Hospital of Traditional Chinese Medicine in Pudong New Area were divided into observation group and reference group by random number table method.60 cases in reference group were treated with Montelukast sodium orally.60 cases in observation group were treated with strengthening spleen and supplementing lung prescription orally.The clinical efficacy,occurrence of adverse reactions,recurrence rate and changes of clinical symptom scores before and after the treatment were compared between the two groups.Results After treatment,the scores of clinical symptoms in the two groups were lower than those before treatment,the scores in the observation group were lower than those in the reference group,and the difference was statistically significant(P<0.05).The total effective rate was 90.00%(54/60)in the observation group and 71.67%(43/60)in the reference group,and the difference was statistically significant(P<0.05).The recurrence rate was 48.33%(29/60)in the reference group and 21.67%(13/60)in the observation group.There was a significant difference in the recurrence rate between the two groups(P<0.05).Conclusion The self-made strengthening spleen and supplementing lung prescription can improve the clinical symptoms and reduce the recurrence rate of children with asthma of lung qi deficiency type.