宫腹腔镜联合手术配合中药口服及灌肠治疗输卵管阻塞性不孕临床观察

Observation on the Clinical Effect of Hysteroscopy-laparoscopy and Operation Combined with Oral Administration of Chinese Medicine and Enema in the Treatment of Tubal Obstructive Infertility

目的观察临床利用宫腹腔镜联合手术配合中药口服及灌肠治疗输卵管阻塞性不孕的临床效果。方法选取2016年1月—2020年5月输卵管阻塞性不孕58例患者,根据不同治疗方法分为试验组和对照组:试验组32例,行宫腹腔镜联合手术,术后进行中药口服及灌肠治疗;对照组26例,未行宫腹腔镜联合手术或术后未成功复通一侧输卵管,术后配合西药消炎类药物口服及静滴治疗,2组均观察患者治疗后6、12、24个月输卵管复通效果及妊娠率。结果治疗后6、12、24个月随访,试验组输卵管复通有效率为100.0%(32/32)高于对照组有效率84.6%(22/26),差异具有统计学意义(P<0.05);治疗后6、12、24个月随访,试验组妊娠率为96.9%(31/32)高于对照组61.5%(16/26),差异具有统计学意义(P<0.05)。结论宫腹腔镜联合手术配合中药口服及灌肠治疗输卵管阻塞性不孕临床用药效果明显,值得推广。

Objective To observe the clinical effect of hysteroscopy-laparoscopy and operation combined with oral administration of Chinese medicine and enema in the treatment of tubal obstructive infertility. Methods A total of 58 patients with tubal obstructive infertility from January 2016 to May 2020 were selected and divided into experimental group and control group according to different treatment methods. The experimental group of 32 cases received hysteroscopy-laparoscopy and combined with oral administration of Chinese medicine and enema. The control group of 26 cases did not undergo laparoscopic combined surgery or failed to successfully reconstruct one side of the fallopian tube after operation, and was treated with oral treatment of western anti-inflammatory drugs after operation. The effect of tubal recanalization and pregnancy rate after 6, 12 and 24 months were observed. Results After treatment of 6, 12and 24 months, the effective rate of tubal recanalization in experimental group was 100.0%(32/32), which was higher than that in control group(84.6%, 22/26), and the difference was statistically significant(P<0.05). After treatment of 6, 12 and 24 months, the pregnancy ratio in experimental group was 96.9%(31/32), which was higher than that in control group(61.5%, 16/26), and the difference was statistical significance(P<0.05). Conclusion Laparoscopic operation combined with oral administration of Chinese medicine and enema in the treatment of tubal obstructive infertility has significantly clinical effect, and is worthy of promotion.