早期四级康复训练在ICU获得性衰弱患者中的应用效果

Application effects of early four-level rehabilitation training in patients with ICU acquired weakness

目的:观察早期四级康复训练在重症监护室(ICU)获得性衰弱患者中的应用效果。方法:选取2019年1月至2020年12月该院收治的84例ICU获得性衰弱患者进行前瞻性研究,按照随机数字表法分为对照组和观察组各42例。对照组实施常规康复训练,观察组实施早期四级康复训练,比较两组训练前后肌力状态[医学研究理事会评分(MRC-score)]、炎性因子[C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]水平和肢体功能[Fugl-Meyer运动功能评定量表(FMA)]。结果:训练后,两组MRC-score和FMA评分均高于训练前,且观察组高于对照组,差异有统计学意义(P<0.05);训练后,两组CRP、IL-6、TNF-α水平均低于训练前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论:早期四级康复训练可提高ICU获得性衰弱患者的MRC-score和FMA评分,降低炎性因子水平,效果优于单纯常规康复训练。

Objective:To observe application effects of early four-level rehabilitation training in patients with intensive care unit(ICU)acquired weakness.Methods:84 patients with ICU acquired weakness who were admitted to our hospital from January 2019 to December 2020 were selected for the prospective study and were divided into control group and observation group according to the random number table method,42 cases in each group.The control group was given routine rehabilitation training,while the observation group used the early four-level rehabilitation training on the basis of that of the control group.The muscle strength status[medical research council score(MRC-score)],the inflammatory factor levels[C-reactive protein(CRP),interleukin-6(IL-6),tumor cell necrosis factor-α(TNF-α)],and the limb function[Fugl-Meyer motor assessment scale(FMA)]were compared between the two groups before and after the training.Results:After the training,the MRC-scores and the FMA scores of the two groups were higher than those before the training,those of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).After the training,the levels of CRP,IL-6 and TNF-αin the two groups were lower than those before the training,those of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusions:On the basis of the routine rehabilitation training,the early four-level rehabilitation training can improve the MRC-scores and the FMA scores and reduce the inflammatory factor levels in the patients with ICU acquired weakness.Moreover,it is superior to single routine rehabilitation training.