散发型帕金森综合征的遗传学研究进展

Advances in genetic research of sporadic Parkinson’s syndrome

帕金森综合征包括继发性帕金森综合征、帕金森叠加综合征和遗传变性帕金森综合征,是目前临床尚无法完全根治的神经系统疾病,因此,临床针对此类疾病开展多种形式的研究以期待能够为帕金森患者提供理想的治疗和康复效果。虽然帕金森病病因复杂,目前临床仍无法完全根治,但帕金森综合征与帕金森病不同,其病因明确,尤其是血管性帕金森综合征被证实具有一定的遗传学且多为散发型。随着临床遗传学的不断发展和进步,针对散发型帕金森综合征的遗传学研究得到广泛的关注和重视,且为临床相关治疗研究提供了重要的参考依据。本研究对散发型帕金森综合征的遗传学相关研究进行综述,以期待能够为临床提供相关参考依据。

Parkinson’s syndrome includes secondary Parkinson’s syndrome,Parkinson’s superposition syndrome and genetic degenerative Parkinson’s syndrome.It is a neurological disease that cannot be completely cured in clinic.Therefore,various forms of clinical research are carried out for this kind of disease in order to provide ideal treatment and rehabilitation effects for Parkinson’s patients.Although the current clinical Parkinson’s disease can not be completely cured and the etiology is complex,Parkinson’s syndrome is different from Parkinson’s disease.Its etiology is clear,especially vascular Parkinson’s syndrome has been proved to have certain genetics and most of them are sporadic.With the continuous development and progress of clinical genetics,genetic research on sporadic Parkinson’s disease has received extensive attention and attention,and provides an important reference for clinical treatment research.This study reviews the genetics related research of sporadic Parkinson’s syndrome,in order to provide relevant reference basis for clinical practice.