血液生化指标与颈动脉支架血管成形术后再狭窄的研究进展

Correlation between blood biochemical indexes and restenosis after carotid artery implantation

支架内再狭窄的主要原因是血管内细胞的损伤、增生和同型半胱氨酸、血脂迁移,血栓形成和炎症反应。C-反应蛋白、血小板、中性粒细胞与淋巴细胞比值、总胆红素、纤维蛋白原等血液指标,近年来被认为是预测颈动脉支架成形术后支架内再狭窄的重要指标。本文主要讨论这些指标参与颈动脉支架成形术后支架内再狭窄中的病理生理机制及其对支架内再狭窄的预测价值。

The main causes of restenosis after artery stent implantation include the cell injury,proliferation,migration and thrombosis,inflammation.Some blood incdications as C-reactive protein(CRP),platelets,neutrophil-lymphocyte Ratio(NLR),total bilirubin,fibrinogen,homocysteine,lipids have been considered to be important predict indicators of restenosis after carotid artery implantation in recent years.The paper mainly discusses the involvement of these indicators in the pathophysiological mechanism of restenosis after carotid artery stent implantation and their predictive value for it.