基于处方模板的食管癌围手术期动态营养支持的建立及应用评价

Establishment and Application Evaluation of Perioperative Dynamic Nutrition Support for Esophageal Cancer Patients Based on Prescription Templates

目的:评价基于处方模板的食管癌围手术期动态营养支持治疗的有效性、安全性及经济性。方法:将2019年4~7月于我院实施基于处方模板的围手术期动态营养支持模式的食管癌患者作为实验组,将2018年4~7月于我院实施传统围手术期营养支持模式的食管癌患者作为对照组,比较两组患者住院期间营养指标、术后胃肠功能恢复时间、并发症发生率、住院时间及药品费用等指标。结果:实验组患者术后第7 d的血清白蛋白、前白蛋白水平均高于对照组(P<0.05)。与对照组相比,实验组患者平均住院天数更短(P<0.05),术后胃肠功能恢复时间差异无统计学意义(P>0.05)。实验组胃肠道并发症发生率低于对照组(P<0.05),感染及吻合口瘘等并发症发生率与对照组相比差异无统计学意义(P>0.05)。实验组患者住院期间药品费用较对照组有所降低,但差异无统计学意义(P>0.05)。结论:基于处方模板的围手术期动态营养支持的建立能有效改善食管癌患者营养状态,降低术后胃肠道并发症的发生率,同时缩短住院时间。

Objective:To evaluate the effectiveness,safety and economy of perioperative dynamic nutrition support for esophageal cancer patients based on prescription templates.Methods:Esophageal cancer patients who received perioperative dynamic nutrition support based on prescription templates in our hospital from April 2019 to July 2019 were seclected as the experimental group,and esophageal cancer patients who received the traditional perioperative nutrition support in our hospital from April 2018 to July 2018 were selected as the control group.The nutrition indicators,postoperative gastrointestinal function recovery time,occurrence rate of complication,duration of hospital stays and drug expense during the hospitalization were compared between the two groups.Results:The serum albumin and pre-albumin levels of patients in the experimental group were higher than those in the control group on the seventh day after surgery(P<0.05).The average duration of hospital stays of the experimental group was shorter than that of the control group(P<0.05).There was no statistical difference in the postoperative recovery time of gastrointestinal function between the two groups(P>0.05).The incidence of gastrointestinal complications in the experimental group was less than that in the control group(P<0.05),and there was no statistical difference in the incidence of complications such as infection and anastomotic fistula between the two groups(P>0.05).The drug expense during the hospitalization of the experimental group were less than those in the control group,but the difference was not statistically significant(P>0.05).Conclusion:The establishment of perioperative dynamic nutrition support based on prescription templates can effectively improve the nutritional status of patients with esophageal cancer,decrease the incidence of postoperative gastrointestinal complications and shorten hospital stays.