^(68)Ga-PSMA PET检查诊断前列腺癌患者淋巴结转移的研究进展

Research progress of detection of lymph node metastases by ^(68)Ga-PSMA PET in prostate cancer patients

随着^(68)Ga-PSMA PET技术在前列腺癌患者诊断中的应用,对淋巴结转移(LNMs)的诊断逐渐成为研究热点之一。目前,^(68)Ga-PSMA PET对前列腺癌LNMs的诊断主要应用于初诊患者和复发患者,与传统影像学检查相比其敏感性、特异性、准确性均较高,并可对前列腺癌的临床诊治策略产生重大影响。本文总结^(68)Ga-PSMA PET技术在前列腺癌LNMs诊断中的研究进展。

With wide application of ^(68)Ga-prostate specific membrane antigen(PSMA)positron emission tomography(PET)technology in the diagnosis of prostate cancer(PCa),researchers have paid more attention to nodal staging in PCa by ^(68)Ga-PSMA PET.Currently,^(68)Ga-PSMA PET has been used to detect lymph node metastases(LNMs)in primary prostate cancer patients and recurrent prostate cancer patients.Compared with the traditional imaging techniques,^(68)Ga-PSMA PET can detect LNMs with higher sensitivity,specificity and accuracy,which has great impact on treatment management of PCa patients.This article reviewed the research progress of detection of LNMs by ^(68)Ga-PSMA PET in prostate cancer patients.