不同对接时间对双气囊小肠镜检查结果及安全性的影响

Influence on the results and safety of double-balloon enteroscopy at different combination time

目的评估不同对接时间对双气囊小肠镜检查结果的影响及安全性。方法2019年4月—2020年8月于南京鼓楼医院完成经口联合经肛小肠镜检查的患者分为同日对接组与非同日对接组。比较两组患者小肠镜对接率、经口小肠镜时间、经肛小肠镜时间、对接总时间、不良事件、住院天数及住院费用。结果纳入患者119例,除外小肠镜检查发现小肠狭窄无法完成对接者23例,96例患者中,同日组对接率92.9%(39/42),非同日组对接率74.1%(40/54),组间差异有统计学意义(χ^(2)=4.390,P=0.036)。同日组与非同日组比较,经肛小肠镜时间[(35.59±23.29)min比(55.10±19.04)min,t=-4.080,P<0.001]、对接总时间[(89.10±27.82)min比(114.20±24.55)min,t=-4.254,P<0.001]、住院天数[(9.24±3.76)d比(11.76±4.41)d,t=-2.599,P=0.011],差异均有统计学意义。两组患者经口小肠镜时间、住院费用、不良事件发生率差异均无统计学意义。结论双气囊小肠镜同一日对接方法可提高小肠镜对接率、缩短检查时间、降低平均住院日,值得在临床中广泛推广应用。

Objective To evaluate the influence on the results and safety of double-balloon enteroscopy(DBE)at different combination time.Methods Patients who received combined DBE procedures in Nanjing Drum Tower Hospital from April 2019 to August 2020 were divided into the one-day combination group and the non-one-day combination group.The complete enteroscopy rate,time of anterograde approach,time of retrograde approach,total time of combined approach,adverse events,hospital stay and cost were compared.Results Among 119 patients who received DBE,23 patients were excluded due to small intestinal stenosis.The complete enteroscopy rate was 92.9%(39/42)in the one-day group and 74.1%(40/54)in the non-one-day group,showing significant difference(χ^(2)=4.390,P=0.036).There were significant differences in the time of retrograde approach(35.59±23.29 min VS 55.10±19.04 min,t=-4.080,P<0.001),total time of combined approach(89.10±27.82 min VS 114.20±24.55 min,t=-4.254,P<0.001),hospital stay(9.24±3.76 d VS 11.76±4.41 d,t=-2.599,P=0.011)between the two groups.There were no significant differences in the time of anterograde approach,hospital cost or adverse events between the two groups.Conclusion Combined DBE on one day yields a higher complete enteroscopy rate,less examination time and less hospital stay,which is worth of clinical application.