脑健康康复系统在轻度认知障碍患者居家认知训练中的应用研究

Application of brain health rehabilitation training system in home-based cognitive training for patients with mild cognitive impairment

目的 探讨脑健康康复系统在轻度认知障碍(mild cognitive impairment, MCI)患者居家认知训练中的应用效果。方法 选取2019年6月至2021年4月首都医科大学宣武医院住院的MCI患者130例,采用随机数字表法分为对照组和干预组,每组65例。对照组发放《轻度认知障碍居家认知训练手册》于出院后居家自行学习,干预组采用脑健康康复系统进行居家认知训练,30 min/次,5次/周,共24周。干预前和干预24周后,采用简易精神状态检查量表(mini-mental state examination, MMSE)、蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、Zarit照顾者负担量表(Zaritburdeninterview,ZBI)和积极感受量表(positiveaspectsof caregiving,PAC)对两组患者的整体认知功能、照顾者负担和积极感受进行评价。结果 干预24周后,干预组MMSE评分和MoCA评分显著高于对照组[(23.25±2.95)分比(19.54±4.19)分,(18.55±3.02)分比(15.08±4.34)分],ZBI评分显著低于对照组[(28.27±10.59)分比(40.12±11.11)分],差异均有统计学意义(P<0.05),两组PAC评分比较,差异无统计学意义(P>0.05)。结论 采用脑健康康复系统进行居家认知训练可以延缓MCI患者整体认知功能下降,还可以减轻照顾者的照顾负担。

Objective To explore the effect of brain health rehabilitation training system in home-based cognitive training for patients with mild cognitive impairment(MCI). Methods A total of 130 MCI patients hospitalized in Xuanwu Hospital, Capital Medical University from June 2019 to April 2021 were selected and divided into control group and intervention group by random number table method, with 65 cases in each group. In the control group, a handbook of home-based cognitive training for MCI was distributed after discharge from the hospital for self-learning at home. In the intervention group, the brain health rehabilitation training system for home cognitive training were used, 30 min/time, 5 times/week, for 24 weeks. Before and 24 weeks after intervention, the mini-mental state examination(MMSE), Montreal cognitive assessment(MoCA), Zarit burden interview(ZBI), and positive aspects of caregiving(PAC) were used to evaluate the overall cognitive function, care-giver burden and positive feelings of the two groups of patients. Results After 24 weeks of intervention, the MMSE score and MoCA score in the intervention group were significantly higher than those in the control group [(23.25±2.95) points vs.(19.54±4.19) points,(18.55±3.02) points vs.(15.08±4.34) points]. The ZBI score was significantly lower than that in the control group [(28.27 ±10.59) points vs.(40.12±11.11) points], the differences were statistically significant(P<0.05). And there was no significant difference in the PAC score between the two groups(P>0.05). Conclusions Home-based cognitive training using a brain health rehabilitation system can delay the overall cognitive decline in MCI patients and al so reduce the care-giver burden.