当归芍药散治疗女性尿道综合征疗效

Effect of Danggui Shaoyao Powder in the Treatment of Female Urethral Syndrome

目的:观察当归芍药散加减治疗女性尿道综合征的疗效。方法:选取北京中医药大学房山医院2011年1月至2021年12月期间收治的254例女性尿道综合征患者,随机分为对照组与观察组。其中观察组138例用当归芍药散加减治疗,对照组116例用西药对症治疗,观察两组患者中医症状积分、膀胱过度活动症问卷表(OABSS)、生活质量评分(QOL)变化情况、总有效率情况及不良反应发生情况。结果:两组患者治疗后的中医症状积分均有不同程度下降,且观察组患者治疗后的中医症状积分低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后OABSS、QOL评分均有不同程度降低,且观察组患者的OABSS、QOL评分低于对照组,差异具有统计学意义(P<0.05)。观察组患者治疗总有效率为93.48 %,高于对照组的78.45 %,差异具有统计学意义(P<0.05)。两组患者治疗前后均进行血常规、肝肾功能、心电图等常规检查,均未发现与本研究相关的不良反应。结论:当归芍药散加减治疗女性尿道综合征疗效显著,能有有效改善临床症状及OABSS、QOL评分。

Objective To observe the therapeutic effect of Danggui Shaoyao powder treatment of female urethral syndrome.Methods A total of 254 female patients with urethral syndrome admitted to Fangshan Hospital of Beijing University of Chinese Medicine from January 2011 to December 2021 were randomly divided into a control group and an observation group.Among them,138 cases in the observation group were treated with Danggui Shaoyao powder plus or minus therapy,and 116 cases in the control group were treated with western medicine.The changes of traditional Chinese medicine (TCM) symptom score,overactive bladder symptom score (OABSS),quality of life score (QOL),total effective rate and incidence of adverse reactions in the two groups were observed.Results The scores of TCM symptoms in the two groups decreased to varying degrees after treatment,and the scores of TCM symptoms in the observation group were lower than those in the control group,with statistical significances (P < 0.05).OABSS and QOL scores in the two groups decreased to varying degrees after treatment,and OABSS and QOL scores in the observation group were lower than those in the control group,the differences were statistically significant (P < 0.05).The total effective rate of the observation group was 93.48%,higher than 78.45% of the control group,the difference was statistically significant (P < 0.05).Routine examinations of blood routine,liver and kidney function and electrocardiogram were performed before and after treatment in the two groups,and no adverse reactions related to this study were found.Conclusion Danggui Shaoyao powder has a significant effect in the treatment of female urethral syndrome,and can effectively improve the clinical symptoms,OABSS and QOL scores.