胃癌术后化疗患者癌因性疲乏现状及其影响因素分析

Cancer-related fatigue status among gastric carcinoma patients underwent postoperative chemotherapy and analyzing its influencing factors

目的 分析胃癌术后化疗患者癌因性疲乏现状及其影响因素。方法 选择2021年4月—2022年3月本院肿瘤内科收治的120例胃癌术后化疗患者作为研究对象,对胃癌术后化疗患者进行问卷调查。单因素分析:比较不同社会人口学特征胃癌术后化疗患者癌因性疲乏水平的差异,Pearson相关分析痛苦表露量表、领悟社会支持量表、心理弹性量表与癌因性疲乏之间的关系;多因素分析:以癌因性疲乏为因变量,以患者的一般资料、痛苦表露、领悟社会支持、心理弹性为自变量建立多元逐步回归。结果 胃癌术后化疗患者癌因性疲乏分数为(39.24±9.44)分,其中患者的年龄、文化程度、家庭人均月收入与胃癌术后化疗患者癌因性疲乏的发生有关(P<0.05);经Pearson检验得出癌因性疲乏与痛苦表露呈正相关(r=0.432),与领悟社会支持、心理弹性呈负相关(r=-0.585,r=-0.539);多元回归分析显示年龄、文化程度、家庭收入、领悟社会支持、心理弹性是胃癌术后化疗患者的独立影响因素(P<0.05)。结论 60岁以上、文化程度低、收入低的胃癌术后化疗患者易发生癌因性疲乏,增加社会支持,提高心理弹性可降低患者癌因性疲乏的发生。

Objective To analyze the status cancer-induced fatigue among patients suffered with gastric cancer and underwent postoperative chemotherapy, and its influencing factors.Methods From April 2021 to March 2022, 120 patients suffered with gastric cancer undergoing chemotherapy after operation in the department of oncology of the hospital were enrolled as study subjects. Questionnaire survey was carried out among the patients. Univariate analysis: To compare the levels of cancer-related fatigue among gastric cancer patients with different social demographic characteristics after chemotherapy. Pearson correlation analysis was conducted on the relationship between the pain disclosure scale, perceived social support scale, mental resilience scale and cancer-related fatigue. Multivariate analysis: using cancer-related fatigue as the dependent variable and patients’ general information, distress disclosure, perceived social support, and psychological resilience as independent variables, multiple step step regression was established.Results The score of cancer-induced fatigue was(39.24±9.44). Among them, the age, education level and monthly family income of patients were associated with the incidence of cancer-induced fatigue in patients with gastric cancer after chemotherapy(P<0.05). According to the results of Pearson correlation analysis, there was a positive correlation between cancer-induced fatigue and pain expression(r=0.432). It was negatively correlated with perceived social support and resilience(r=-0.585, r=-0.539). Multiple regression analysis showed that age, education level, family income, understanding social support and mental resilience were the independent influencing factors of postoperative chemotherapy for gastric cancer patients(P<0.05).Conclusions Patients over 60 years old, with low education level and low income are prone to cancer-related fatigue after chemotherapy. Increasing social support and improving psychological resilience could reduce the incidence of cancer-related fatigue.