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以急性精神障碍起病的桥本脑病(附1例报告及文献复习)

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摘要 目的探讨桥本脑病的临床表现、辅助检查、诊断及治疗,以提高临床医生对桥本脑病的认识。方法回顾性分析1例首发症状为急性精神障碍起病桥本脑病患者的临床资料、辅助检查及诊治过程,结合相关文献进行分析总结。结果患者女性,68岁,因“精神行为异常6 h”入院。主要表现为胡言乱语、幻视、记忆力下降,等。简易精神状态量表(MMSE)评分6分,血清抗甲状腺过氧化物酶抗体和促甲状腺素受体抗体、脑脊液蛋白明显增高,脑脊液二代测序及自身免疫性脑炎抗体谱阴性,诊断为桥本脑病。予激素治疗后症状好转。出院后随访:精神恢复良好,日常生活能力恢复。结论桥本脑病较为罕见,临床医生对桥本脑病认识不足,较易误诊。血清甲状腺抗体增高是桥本脑病最重要的诊断依据之一,该病大多预后良好,早期检测甲状腺功能及抗体有助于识别该病。
出处 《中国临床神经科学》 2022年第3期320-323,共4页 Chinese Journal of Clinical Neurosciences
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