结肠息肉围手术期质子泵抑制剂使用合理性分析

Analysis of rationality of proton pump inhibitors in perioperative colon polyps

目的对某院消化内科行结肠息肉切除术患者围手术期使用质子泵抑制剂(proton pump inhibitors,PPIs)进行合理性分析,为PPIs临床合理应用提供依据与参考。方法记录某院HIS系统中2020年9月~2020年11月在消化内科行结肠息肉切除术的患者信息,采用回顾性分析方法,对这部分患者围手术期PPIs应用情况进行合理性评价,包括适应证、药物选择、用药疗程等。结果抽取的354份病例中28.53%患者有预防用药指征,注射用泮托拉唑钠占64.69%;预防用药的平均疗程为2.88 d。结论该院消化内科结肠息肉切除术围术期使用PPIs预防性用药中,仍存在一些不合理用药现象。医院宜制订结肠息肉围术期PPIs预防用药标准,以规范临床用药,进一步促进PPIs合理使用。

Objective The rationality of perioperative use of Proton pump inhibitors(PPIs)in patients undergoing colonic polypectomy in the department of Gastroenterology of a hospital was analyzed to provide basis and reference for rational clinical application of PPIs.Methods The information of patients who underwent colonic polypectomy in the department of Gastroenterology in HIS system of the hospital from September to November 2020 was recorded,and the rationality of PPIs application in perioperative period of these patients was evaluated by retrospective analysis,including indications,drug selection and medication course,etc.Results 354 cases were selected,among which 28.53% had indications of preventive medication,and pantoprazole sodium for injection accounted for 64.69%.The average course of prophylactic medication was 2.88 days.Conclusion In the department of Gastroenterology of the hospital,there are still some irrational use of PPIs prophylactic drugs in the perioperative period of colon polypectomy.The hospital should establish the standard of PPIs prophylactic medication for colon polyps during perioperative period,so as to standardize clinical medication and further promote the rational use of PPIs.