全程化疼痛护理管理对晚期癌痛患者疼痛情况、用药依从性及生活质量的影响

Effects of whole process pain nursing management on pain situation,medication compliance and quality of life of patients with advanced cancer pain

目的 分析全程化疼痛护理管理在晚期癌痛患者中的应用效果。方法 选取2019年6月至2020年6月我院肿瘤科收治的100例晚期癌痛患者作为研究对象,按照护理方式不同将其分为对照组和观察组,各50例。对照组实施常规护理管理,观察组实施全程化疼痛护理管理。比较两组的疼痛应激指标、疼痛情况、用药依从性及生活质量。结果 干预后,观察组的5-羟色胺(5-HT)、神经肽Y(NPY)、前列腺素E2(PGE2)水平低于对照组,差异具有统计学意义(P<0.05)。干预后,观察组的简明疼痛量表(BPI)评分低于对照组,中文版8条目Morisky用药依从性问卷(MMAS-8)评分高于对照组,差异具有统计学意义(P<0.05)。干预后1个月,观察组的36条简明健康状况调查表(SF-36)评分高于对照组,差异具有统计学意义(P<0.05)。结论 全程化疼痛护理管理可改善晚期癌痛患者的疼痛应激指标,缓解疼痛情况,提高用药依从性及生活质量,可在临床推广和应用。

Objective To analyze the application effect of whole process pain nursing management in patients with advanced cancer pain.Methods A total of 100 patients with advanced cancer pain treated in the oncology department of our hospital from June 2019 to June 2020 were selected as the research objects.According to the different nursing methods,the patients were divided into control group and observation group,with 50 cases in each group.The control group implemented routine nursing management,and the observation group implemented whole process pain nursing management.The pain stress indexes,pain situation,medication compliance and quality of life were compared between the two groups.Results After intervention,the levels of 5-hydroxytryptamine(5-HT),neuropeptide Y(NPY)and prostaglandin E2(PGE2)in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After intervention,the Brief Pain Inventory(BPI)score of the observation group was lower than that of the control group,and the Morisky Medication Adherence Scale(MMAS-8)score was higher than that of the control group,and the differences were statistically significant(P<0.05).One month after intervention,the Medical Outcomes Study Short-Form(SF-36)score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The whole process pain nursing management can improve the pain stress indexes of patients with advanced cancer pain,relieve the pain situation,improve the medication compliance and quality of life,and can be popularized and applied in clinic.