2013—2017年南通市肺癌流行病学特征分析

Analysis of epidemiological characteristics of lung cancer in Nantong City from 2013 to 2017

目的分析2013—2017年南通市肺癌发病和死亡特征,为南通市肺癌综合防控策略的制定提供参考依据。方法利用质控合格的南通市2013—2017年肿瘤登记资料,分别根据城乡和性别计算肺癌发病(死亡)率、年龄别发病(死亡)率以及标化发病(死亡)率等指标,标准人口采用2000年中国普查标准人口和Segi's世界标准人口。采用Joinpoint 4.9.0软件,对2013—2017年肺癌发病(死亡)率和标化发病(死亡)率的变化趋势进行分析。结果2013—2017年南通市肿瘤登记处共报告肺癌新发病例30689例,粗发病率为83.46/10万,中标发病率为35.71/10万,肺癌位居全部恶性肿瘤发病顺位首位,男性中标发病率(45.24/10万)高于女性(25.47/10万),为女性的1.78倍,城市地区中标发病率(39.49/10万)高于农村地区(34.58/10万),为农村地区的1.11倍。城市地区男性肺癌中标发病率均呈下降趋势(P<0.05),而农村地区全人群和女性肺癌中标发病率呈上升趋势(P<0.05)。肺癌发病率随年龄增加呈先上升后下降的趋势,在80~84岁年龄组达到发病高峰(417.82/10万),85岁及以上年龄组有所下降。肺癌死亡病例23806例,粗死亡率为64.74/10万,中标死亡率为26.08/10万,肺癌位居全部恶性肿瘤死亡顺位首位,男性中标死亡率(34.76/10万)高于女性(16.71/10万),为女性的2.08倍,城市地区中标死亡率(26.21/10万)与农村地区中标死亡率(26.05/10万)相当。城市地区全人群肺癌中标死亡率呈下降趋势(P<0.05)。肺癌死亡率随年龄增加呈先上升后下降的趋势,在80~84岁年龄组达到死亡高峰(420.50/10万),85岁及以上年龄组有所下降。结论南通市肺癌发病与死亡率均位居首位,严重危害当地居民健康。要加强健康教育、加大烟草控制宣传力度,持续深入推进肺癌早诊早治等措施,以降低居民肺癌疾病负担。

Objective The aim of this study was to analyze the incidence and mortality characteristics of lung cancer in Nantong city from 2013 to 2017,and to provide a reference for the formulation of comprehensive lung cancer prevention and control strategies in Nantong city.Methods Using the quality-controlled tumor registration data of Nantong city from 2013 to 2017,calculate lung cancer incidence(mortality),age-specific incidence(mortality)and standardized incidence(mortality).Joinpoint 4.9.0 software was used to analyze the changing trend of lung cancer incidence(mortality)from 2013 to 2017.The standard population adopts the 2000 Chinese census standard population and Segi's world standard population.Results In 2013-2017,a total of 30,689 new cases of lung cancer were reported in Nantong Cancer Registry,with the crude incidence of 83.46/100,000 and a standardized incidence of 35.71/100,000.Lung cancer ranked first among all malignant tumors.The standardized incidence of men(45.24/100,000)was higher than that of women(25.47/100,000),which was 1.78 times than that in women.The standardized incidence in urban areas(39.49/100,000)was higher than that in rural areas(34.58/100,000),which was 1.11 times in rural areas.The standardized incidence of lung cancer in urban areas showed a downward trend(P<0.05),while the standardized incidence of lung cancer in the whole population and women from rural areas showed an upward trend(P<0.05).The incidence of lung cancer showed a trend of first increasing and then decreasing with age,reaching a peak in the 80-year-old age group(417.82/100,000),and decreasing in the 85-year-old age group.There were 23,806 deaths from lung cancer,the crude mortality was 64.74/100,000,and the standardized mortality was 26.08/100,000.Lung cancer ranked first among all malignant tumors.The standardized mortality for men(34.76/100,000)was higher than that of women(16.71/100,000),which was 2.08 times than that in women.The standardized mortality in urban areas(26.21/100,000)was comparable to that in rural areas(26.05/100,000).The standardized mortality of lung cancer in the whole population and urban areas showed a downward trend(P<0.05).The mortality of lung cancer showed a trend of first increasing and then decreasing with age,reaching a peak of death in the 80-year-old age group(420.50/100,000),and decreasing in the 85-year-old and above age group.Conclusion The incidence and mortality of lung cancer in Nantong city ranks first,seriously endangering the health of local residents.It is necessary to strengthen health education,increase tobacco control publicity,and continue to promote measures such as early diagnosis and early treatment of lung cancer to reduce the burden of lung cancer disease on residents.