高频彩超对乳腺癌腋窝淋巴结转移的诊断研究

Diagnosis of breast cancer axillary lymph node metastasis by high frequency color Doppler ultrasound

目的探讨应用高频彩超诊断腋窝淋巴结转移的乳腺癌患者价值。方法回顾性分析2019年5月至2020年7月,本院96例经病理学检查确诊为乳腺癌对患者的临床资料,所有患者均给予高频彩超检查,以病理学诊断结果为金标准,比较高频彩超诊断乳腺癌腋窝淋巴结转移与病理学诊断结果的一致性;比较发生腋窝淋巴结转移的乳腺癌患者与未转移的患者血流信号特征;比较发生腋窝淋巴结转移的乳腺癌患者与未转移患者的超声影像特征。结果经病理学诊断证实,60例乳腺癌患者中,25例乳腺癌患者发生腋窝淋巴结转移;高频彩超对乳腺癌腋窝淋巴结转移的诊断结果与病理学诊断结果的一致性较好(Kappa=0.898,P<0.001);乳腺癌腋窝淋巴结转移组血流信号分级高于乳腺癌腋窝淋巴结未转移组,差异有统计学意义(P<0.05);乳腺癌腋窝淋巴结转移组皮质向心性增厚、淋巴结边界模糊、淋巴结内存在钙化征占比均高于乳腺癌腋窝淋巴结未转移组,差异有统计学意义(P<0.05)。结论在乳腺癌患者中,应用高频彩超诊断其发生腋窝淋巴结转移风险效果较好,临床上可依据高频彩超影像特征来辅助诊断,以提高腋窝淋巴结转移的诊断准确度,改善患者预后。

Objective To investigate the value of high-frequency color Doppler ultrasound in the diagnosis of axillary lymph node metastasis in breast cancer patients.Methods The clinical data of 96 patients with breast cancer diagnosed by pathological examination in our hospital from May 2019 to July 2020 were retrospectively analyzed.All patients were given highfrequency color Doppler ultrasonography,and the pathological diagnosis results were used as the gold standard to compare the consistency between the diagnosis of axillary lymph node metastasis of breast cancer by high frequency color Doppler ultrasound and pathological diagnosis;the blood flow signal characteristics of breast cancer patients with axillary lymph node metastasis and patients without metastasis were compared;the ultrasonic imaging characteristics of patients with axillary lymph node metastasis and patients without metastasis of breast cancer were compared.Results It was confirmed by pathological diagnosis that among 60 breast cancer patients,25 breast cancer patients developed axillary lymph node metastasis;the diagnosis results of breast cancer axillary lymph node metastasis by highfrequency color Doppler ultrasound were in good agreement with the pathological diagnosis results(Kappa=0.898,P<0.001);the blood flow signal grade in the breast cancer axillary lymph node metastasis group was higher than that in the breast cancer axillary lymph node nonmetastasized group,the difference was statistically significant(P<0.05);the breast cancer axillary lymph node metastasis group had concentric cortical thickening and lymph node the proportions of blurred borders and calcification signs in lymph nodes were higher than those in the breast cancer group without axillary lymph node metastasis,and the difference was statistically significant(P<0.05).Conclusion In breast cancer patients,the application of high-frequency color Doppler ultrasound to diagnose the risk of axillary lymph node metastasis has a better effect.Clinically,diagnosis can be aided based on the characteristics of high-frequency color Doppler ultrasound,so as to improve the accuracy of the diagnosis of axillary lymph node metastasis and improve the prognosis of patients.