经股动脉介入联合静脉溶栓在急性缺血性脑卒中的应用效果

Application effect of transfemoral artery intervention combined with intravenous thrombolysis in acute ischemic stroke

目的探讨经股动脉介入联合静脉溶栓在急性缺血性脑卒中(AIS)中的应用效果。方法选取2018年1月至2019年9月本院收治的90例AIS患者作为研究对象,采用掷硬币法分为观察组和对照组,每组45例。对照组采用静脉溶栓治疗,观察组采用经股动脉介入联合静脉溶栓治疗,比较两组临床疗效、血管再通率、≤30%血管残余狭窄率、神经功能缺损情况。结果观察组治疗总有效率为97.78%,高于对照组的82.22%,差异有统计学意义(P<0.05)。观察组血管再通率、≤30%血管残余狭窄率均高于对照组,差异有统计学意义(P<0.05)。治疗后,两组美国国立卫生研究院卒中量表(NIHSS)评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论经股动脉介入联合静脉溶栓治疗AIS效果显著,可有效促进血管再通,降低血管狭窄率,且可改善患者神经功能情况,利于患者预后,值得临床推广应用。

Objective To investigate the effect of transfemoral artery intervention combined with intravenous thrombolysis in acute ischemic stroke(AIS).Methods 90 patients with AIS who were admitted to our hospital from January 2018 to September 2019 were selected as the research subjects,and they were divided into observation group and control group by tossing a coin,with 45 cases in each group.The control group was treated with intravenous thrombolysis,and the observation group was treated with transfemoral artery intervention combined with intravenous thrombolysis.The clinical efficacy,vascular recanalization rate,residual stenosis rate of≤30%vessels,and neurological deficit were compared between the two groups.Results The total effective rate of the observation group was 97.78%,which was higher than 82.22%of the control group,and the difference was statistically significant(P<0.05).Vascular recanalization rate and vascular residual stenosis rate of≤30%in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).After treatment,the National Institutes of Health stroke scale(NIHSS)scores in between groups were lower than those before treatment,and the observation group was lower than the control group,and the difference was statistically significant(P<0.05).Conclusion Femoral artery intervention combined with intravenous thrombolysis in the treatment of AIS has a significant effect,can effectively promote vascular recanalization,reduce vascular stenosis rate,and can effectively improve the neurological function of patients,which is beneficial to the prognosis of patients,and is worthy of clinical application.