时差成像技术在临床应用中的进展

Recent advances in time-lapse technology in clinical application

随着对体外胚胎形态学参数、时差动力学参数的认知,时差成像技术(time-lapse technology,TLT)已经进入了一个快速发展的阶段。TLT能实时连续记录胚胎从受精、卵裂、囊胚形成的各项细节图像并发现传统观察胚胎技术不能发现的细节,为胚胎筛选提供依据。此外,TLT还能在临床应用、实验室质量控制中发挥作用。与此同时,TLT在体外胚胎发育分析、人工智能开发中也存在问题,本文将对其进行探讨。

Time-lapse technology(TLT)has entered a stage of rapid development with the recognition of morphological parameters and kinetic parameters of embryos in vitro.TLT can continuously record the detailed images of embryo from fertilization,cleavage and blastocyst formation and find the details that traditional observation embryo technology cannot find,providing the basis for embryo screening.In addition,TLT can also play a role in clinical applications and quality control of laboratory.At the same time,TLT also has some problems in in vitro embryo development analysis and artificial intelligence development,which will be discussed in this paper.