摘要
A catalytic asymmetric hydroxylative dearomatization reaction has been disclosed,and the products can smoothly transform into spiroannulation adducts by simply treated with a base under mild conditions.Novel in-situ generated magnesium catalytic methods are developed by application of combinational ligands.Related concise transformaitons of the spiroannulation adducts have been carried out.
基金
the financial support from the National Natural Science Foundation of China (Nos. 21901092, 21807053)
Innovation Fund for Medical Sciences (No. 2019-12M-5-074)
Program for Chang-jiang Scholars and Innovative Research Team in University (PCSIRT) (No. IRT_15R27)
the Funds for Fundamental Research Creative Groups of Gansu Province (No. 20JR5RA310)
the Fundamental Research Funds for the Central Universities (Nos. lzujbky2020-49, 2021-kb21)
