邢台地区女性饮食习惯与乳腺癌的相关性分析

Correlation Analysis Between Dietary Habit and Breast Cancer of Female in Xingtai Area

目的 分析邢台地区女性饮食习惯与乳腺癌发生的相关性。方法 选择2018-02/2020-06月在作者医院就诊的82例女性乳腺癌患者为病例组,根据年龄(±5岁)进行1∶1配比,选择同期进行乳腺癌筛查的82例健康女性作为对照组。以现场问卷调查方式获取患者一般资料及米饭、面制品、豆类及豆制品等10大类食物近1年的食用频次。比较两组患者资料,以多元有序Logistic回归分析判断各因素的综合作用。结果 单因素分析基础上行多因素Logistic回归分析结果显示:有吸烟史(OR=1.510,95%CI:1.055~2.161)、有饮酒史(OR=1.458,95%CI:1.084~1.960)、有乳腺癌家族史(OR=1.516,95%CI:1.061~2.166)、腌制食品摄入≥2次/周(OR=1.481,95%CI:1.033~2.125)、油炸食品摄入≥2次/周(OR=1.435,95%CI:1.044~1.971)为邢台地区女性乳腺癌患病的危险因素;豆类及豆制品摄入≥2次/周(OR=0.694,95%CI:0.493~0.978)、新鲜果蔬摄入≥2次/周(OR=0.744,95%CI:0.572~0.967)则为保护性因素(P<0.05)。结论 邢台地区女性乳腺癌的发生与腌制食品、油炸食品、豆类及豆制品、新鲜果蔬的摄入频率均有密切的关系,另外吸烟史、饮酒史及乳腺癌家族史也与乳腺癌的发生具有相关性。

Objective To analyze the correlation between dietary habit and breast cancer of female in Xingtai area. Methods A total of 82 female breast cancer patients who were treated in author′s hospital from February 2018 to June 2020 were selected as the case group, and 82 healthy women who were screened for breast cancer during the same period were selected according to 1∶1 ratio of age(±5 years) and were served as control group. General information of patients and the consumption frequency of 10 food categories including rice, flour products, beans and soy products in the past year were obtained by on-site questionnaire surveys. The above-mentioned data of the two groups of patients were compared, and the comprehensive effect of each factor was judged by multivariate ordered Logistic regression analysis. Results Based on single factor analysis, the results of uplink multivariate logistic regression analysis showed that: smoking history(OR=1.510, 95%CI:1.055-2.161), drinking history(OR=1.458, 95%CI:1.084-1.960), family history of breast cancer(OR=1.516, 95%CI:1.061-2.166), intake of pickled food ≥2 times/week(OR=1.481, 95%CI:1.033-2.125), intake of fried food ≥2 times/week(OR=1.435, 95%CI:1.044-1.971) were risk factors for breast cancer among women in Xingtai area. intake of beans and soy products ≥2 times/week(OR=0.694, 95%CI:0.493-0.978), intake of fresh fruits and vegetables ≥2 times/week(OR=0.744, 95%CI:0.572-0.967) were protective factors(P<0.05). Conclusion The incidence of female breast cancer in Xingtai area is closely related to the intake frequency of pickled food, fried food, beans and bean products, fresh fruits and vegetables. In addition, the history of smoking, drinking and family history of breast cancer are also related to the incidence of breast cancer.