肢体抖动短暂性脑缺血发作的研究进展

Recent advance in clinical problems of limb-shaking transient ischemic attack

肢体抖动短暂性脑缺血发作(LS-TIA)是一种罕见的TIA形式,通常以颈内动脉的严重狭窄或闭塞为基础,临床上主要以发作性不自主肢体抖动为特征,一般持续数秒或数分钟,常在运动或站立后发生。目前国内对LS-TIA的研究较少,仅为零星的个案报告,尚无系统的综述和荟萃分析研究,未能引起神经科医生的普遍关注。本文现围绕LS-TIA的发病机制、临床特征、影像学特点及诊治方法综述如下,以期提高临床医生对LS-TIA的早期识别能力及治疗水平。

Limb shaking transient ischemic attack(LS-TIA)is a rare form of TIA,usually based on severe narrowing or occlusion of the internal carotid artery.Clinically,it is mainly characterized by episodic involuntary limb shaking,which generally lasts for several seconds or minutes and often occurs after exercise or standing up.At present,there are few studies on LS-TIA in China,with only sporadic case reports,and without systematic review and meta-analysis studies;and it seems to fail in attracting widespread concern from neurologists.In this paper,the pathogenesis,clinical features,imaging features and diagnosis and treatment methods of LS-TIA are reviewed as follows,in order to improve the level of early recognition and treatment of LS-TIA from clinicians.