多层螺旋CT与磁共振弥散加权成像检查在肢体软组织肿瘤诊断中的比较分析

Comparative analysis of MSCT and MRI-DWI in the diagnosis of soft connective tissue tumors of limbs

目的:探讨多层螺旋CT(MSCT)、磁共振弥散加权成像(MRI-DWI)技术对肢体软组织肿瘤的诊断价值。方法:采用随机数表法选取医院收治的80例肢体软组织肿瘤患者,均行MSCT、MRI-DWI及穿刺病理检查。以病理检查为金标准,比较MSCT及MRI-DWI检查方式的肿瘤表现特征、准确率、灵敏度、特异度、阳性预测值、阴性预测值和表观弥散系数(ADC)值。结果:在80例肢体软组织肿瘤患者病理检查结果中,阳性64例、阴性16例;MSCT检查的真阳性41例(占51.25%)、假阳性7例(占8.75%)、真阴性9例(占11.25%)、假阴性23例(占28.75%);MRI-DWI检查结果中真阳性52例(占65.00%)、假阳性2例(占2.50%)、真阴性14例(占17.50%)、假阴性12例(占15.00%)。MSCT检查准确率、灵敏度、阳性预测值、阴性预测值与MRI-DWI比较,差异有统计学意义(x^(2)=8.025,x^(2)=4.758,x^(2)=6.554,x^(2)=3.965;P<0.05);MRIDWI检查恶性与良性肿瘤组织ADC值比较差异有统计学意义(t=7.985,P<0.05)。结论:MRI-DWI的诊断准确率、灵敏度及阳性预测值均高于MSCT检查,对肢体软组织肿瘤诊断价值更高,可为临床诊断此病提供可靠依据。

Objective:To explore the diagnostic value of multi-slice spiral computed tomography(MSCT)and magnetic resonance imaging-diffusion weighted imaging(MRI-DWI)in soft connective tissue tumors of limbs.Method:80 patients with soft connective tissue tumors of limbs who admitted to hospital were selected by using random number table.And all of them underwent MSCT,MRI-DWI and pathological examination with puncture.The pathological examination was used as golden standard to compare the performance characteristics,accuracy,sensitivity,specificity,positive prediction value,negative prediction value and apparent dispersion coefficient(ADC)value between MSCT examination and MRI-DWI examination.Results:The pathological results indicated that 64case were positive and 16 cases were negative.As the pathological results,the MSCT examination indicated that 41cases were true positive(51.25%),and 7 cases were false positive(8.75%),and 9 cases were true negative(11.25%),and 23 cases were false negative(28.75%).The MRI-DWI examination indicated that 52 cases were true positive(65.00%),and 2 cases were false positive(2.50%),and 14 cases were true negative(17.50%)and 12 cases were false negative(15.00%).The differences of accuracy rate,sensitivity,positive prediction value and negative prediction value between MSCT examination and MRI-DWI examination were significant(x^(2)=8.025,x^(2)=4.758,x^(2)=6.554,x^(2)=3.965,P<0.05).In addition,the difference of ADC value in MRI-DWI examination between malignant and benign tumor tissue was significant(t=7.985,P<0.05).Conclusion:The diagnostic accuracy rate,sensitivity and positive prediction value of MRI-DWI examination are higher than those of MSCT examination,which diagnostic value is higher for soft connective tissue tumors of limbs.It can provide reliable basis for clinical diagnosis of this disease.