脓毒症早期识别的研究进展

Research progress in early identification of sepsis

脓毒症是威胁人类健康的急危重症之一,其发病后的致残率及致死率均处于较高水平,早期发现并尽早治疗脓毒症可以有效降低这一比例。因此,对脓毒症的早期判别已成为国际共识。目前,有很多临床手段及科学研究在脓毒症的识别和评估方面进行了探索,并取得了相应的进展。该文从脓毒症相关标志物、病原体的早期识别、宿主的临床易感性及综合预测模型的构建4个方面对脓毒症早期识别进行系统阐述,以期为临床医务工作者提供参考。

Sepsisis one of the critical illnesses that threaten human health,with aexcessive fee of incapacity and mortality Early detectionand treatment of sepsis can effectively reduce this ratio.Therefore,the early identification of sepsis has end up an worldwide consensus.At present,there are many clinical methods and scientific researches that have been explored in the identification and evaluation of sepsis and corresponding progress has been made.This article reviews the early identification of sepsis in four aspects:sepsis-related markersearly identification of pathogens,clinical susceptibility of hosts and construction of a comprehensive prediction model,in order to provide reference for clinical medical workers.